Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 4/20 | 1.00 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.66 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.66 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.66 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.66 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.66 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.66 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.66 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.66 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.66 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | CES2 | O00748 | 1/20 | 0.59 |
| ▸ | CES1 | P23141 | 1/20 | 0.59 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 3/20 | 0.57 |
| ▸ | CA2 | P00918 | 3/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL17626749 | 0.98 | GSK3B (0.96) | GSK3BHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL2773360 | 0.94 | GSK3B (0.89) | GSK3BHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7390281 | 0.94 | GSK3B (0.89) | GSK3BHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8103554 | 0.88 | GSK3B (0.77) | GSK3BHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8557179 | 0.87 | GSK3B (0.75) | GSK3BMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL4328500 | 0.85 | GSK3B (0.73) | GSK3BHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7314253 | 0.84 | GSK3B (0.72) | GSK3BHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL571370 | 0.83 | GSK3B (0.71) | GSK3BHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL31065275 | 0.83 | GSK3B (0.71) | GSK3BHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL153386 | 0.83 | ALDH1A1 (0.76) | GSK3BHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2242 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250333698-A1 | SIRPa DEFICIENT MACROPHAGES FOR TREATING CANCER | UNIV GEORGIA STATE RES FOUND (US) | 2025-10-30 | — | — | US | claimed |
| CN-120081843-A | Fluorescent probe for quantitatively detecting NO in exhaled breath, and preparation method and application thereof | 阜阳师范大学 | 2025-06-03 | — | — | CN | claimed |
| CN-119930621-A | Fungus-inhibiting matrine hydrazine thiazole derivative and preparation method and application thereof | 南京林业大学 | 2025-05-06 | — | — | CN | claimed |
| WO-2025059259-A1 | NEW PROCESS FOR PHENYLEPHRINE AND SALBUTAMOL AND RELATED COMPOUNDS VIA ASYMETRIC TRANSFER HYDROGENATION OF UNPROTECTED AMINO KETONES | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2025-03-20 | — | — | WO | claimed |
| CN-118930487-A | 1,3, 5-Trisubstituted pyrazole compound and preparation method thereof | 赣南师范大学 | 2024-11-12 | — | — | CN | claimed |
| CN-118908971-A | Oxygen bridge bicyclo- [2.2.1] -heptene compound containing different sulfonamide nitrogen atom substituents, and preparation method and application thereof | 湖北大学 | 2024-11-08 | — | — | CN | claimed |
| EP-4423251-A1 | SIRP ALPHA DEFICIENT MACROPHAGES FOR TREATING CANCER | Georgia State University Research Foundation, Inc. (US) | 2024-09-04 | — | — | EP | claimed |
| CN-118324975-A | Phenothiazine skeleton macromolecule cationic photoinitiator and preparation method and application thereof | 江南大学 | 2024-07-12 | — | — | CN | claimed |
| CN-118176293-A | SIRPalpha-deficient macrophages for the treatment of cancer | 佐治亚州立大学研究基金会公司 | 2024-06-11 | — | — | CN | claimed |
| CN-115557865-B | Thioether-promoted cysteine-based bioconjugate method | 南京工业大学 | 2024-05-14 | — | — | CN | claimed |
| WO-2006079090-A2 | PROCESS FOR THE PREPARATION OF FENOLDOPAM MESYLATE | SICOR INC. (US) | 2006-07-27 | — | — | WO | claimed |
| JP-2004505888-A | — | — | 2004-02-26 | — | — | JP | claimed |
| EP-1263763-A2 | TUBULIN BINDING LIGANDS AND CORRESPONDING PRODRUG CONSTRUCTS | BAYLOR UNIVERSITY (US) | 2002-12-11 | — | — | EP | claimed |
| US-20020061895-A1 | 6-fluoro-1,4-dihydro-7-[4-(2-hydroxyiminoethyl)-1-piperazinyl]-4-oxoquinoline-3-carboxylic acid derivatives, their preparation and pharmaceutical compositions | PHARMACEUTICAL INDUSTRY TECHNOLOGY | 2002-05-23 | — | — | US | claimed |
| US-20020055643-A1 | Tubulin binding ligands and corresponding prodrug constructs | MATEON THERAPEUTICS, INC. | 2002-05-09 | — | — | US | claimed |
| WO-2001068654-A2 | TUBULIN BINDING LIGANDS AND CORRESPONDING PRODRUG CONSTRUCTS | BAYLOR UNIVERSITY (US) | 2001-09-20 | — | — | WO | claimed |
| EP-0674233-B1 | Recording sheets | XEROX CORP (US) | 2000-05-24 | — | — | EP | claimed |
| US-5928765-A | Recording sheets | XEROX CORPORATION (US) | 1999-07-27 | — | — | US | claimed |
| EP-0674233-A2 | Recording sheets | XEROX CORPORATION (US) | 1995-09-27 | — | — | EP | claimed |
| US-4328356-A | Process for preparing esters of arylacetic acids from alpha-halo-alkylarylketones | MONTEDISON S.P.A. (IT) | 1982-05-04 | — | — | US | claimed |