Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.72 |
| ▸ | MMP1 | P03956 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.61 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.61 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.61 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.61 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.61 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.61 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.61 |
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11281722 | 0.89 | PDE4B (0.70) | GSK3BMMP1MAPTPDE4BNPC1 | |
| SCHEMBL16552644 | 0.88 | MMP1 (0.76) | GSK3BMMP1MAPTPDE4BNPC1 | |
| SCHEMBL8539989 | 0.87 | HDAC8 (0.69) | GSK3BMMP1MAPTPDE4BNPC1 | |
| SCHEMBL7740667 | 0.87 | HDAC8 (0.69) | GSK3BMMP1MAPTPDE4BNPC1 | |
| SCHEMBL7392111 | 0.87 | HDAC8 (0.69) | GSK3BMMP1MAPTPDE4BNPC1 | |
| SCHEMBL2845184 | 0.85 | MAPT (0.66) | GSK3BMMP1MAPTPDE4BNPC1 | |
| SCHEMBL10648612 | 0.84 | CYP1A2 (0.72) | GSK3BMMP1MAPTPDE4BNPC1 | |
| SCHEMBL4082864 | 0.84 | PDE4B (0.86) | GSK3BMMP1MAPTPDE4BNPC1 | |
| SCHEMBL202055 | 0.84 | GSK3B (1.00) | GSK3BMMP1MAPTPDE4BNPC1 | |
| SCHEMBL3171960 | 0.84 | PDE4B (0.79) | GSK3BMMP1MAPTPDE4BNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260118361-A1 | FLUOROGENIC BIOCONJUGATION OF CYCLOPROPANOL-BASED FLUOROPHORES FOR BIOLOGICAL APPLICATIONS | UNIV SOUTH CAROLINA (US) | 2026-04-30 | — | — | US | disclosed |
| US-20250129116-A1 | CYCLOPROPANOL AS A BIOORTHOGONAL WARHEAD FOR ELECTROCHEMICALLY CONTROLLED BIOCONJUGATION APPLICATIONS | UNIVERSITY OF SOUTH CAROLINA | 2025-04-24 | — | — | US | disclosed |
| CN-105315319-B | Hepatitis C virus inhibitor and application thereof | 南京圣和药业股份有限公司 | 2020-11-20 | — | — | CN | disclosed |
| US-4845100-A | WITH HYPOTENSIVE AND ANTIINFLAMMATORY ACTIVITY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-07-04 | — | — | US | disclosed |
| US-4818431-A | ELECTROOPTICAL DISPLAY ELEMENTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-04-04 | — | — | US | disclosed |
| EP-0117476-B1 | TETRAHYDROPYRANES | MERCK PATENT GmbH (DE) | 1987-09-16 | — | — | EP | disclosed |
| EP-0202760-A2 | Carbostyril derivatives and salts thereof, processes for preparing the same and cardiotonic composition containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-11-26 | — | — | EP | disclosed |
| EP-0117476-A1 | Tetrahydropyranes | MERCK PATENT GmbH (DE) | 1984-09-05 | — | — | EP | disclosed |
| US-4000275-A | BENZIMIDAZO(2,1-B) QUINAZOLIN-12(6H)ONES | ELI LILLY AND COMPANY (US) | 1976-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250129116-A1 | CYCLOPROPANOL AS A BIOORTHOGONAL WARHEAD FOR ELECTROCHEMICALLY CONTROLLED BIOCONJUGATION APPLICATIONS | CBR3, CBR1, BBOX1 | GSK3B 2357/4885MMP1 2304/4885MAPT 4280/4885 |
| US-20260118361-A1 | FLUOROGENIC BIOCONJUGATION OF CYCLOPROPANOL-BASED FLUOROPHORES FOR BIOLOGICAL APPLICATIONS | QSOX1, CBR1, CBR3 | GSK3B 4730/4885MMP1 469/4885MAPT 4109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.