Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 7/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 7/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.34 |
| ▸ | ABCC1 | P33527 | 5/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20205632 | 0.94 | PRKDC (0.36) | CYP1A1CYP1B1CYP1A2ABCC1ABCG2 | |
| SCHEMBL20205388 | 0.92 | TDP1 (0.34) | CYP1A1CYP1B1CYP1A2ABCC1ABCG2 | |
| SCHEMBL20205638 | 0.89 | TDP1 (0.37) | CYP1A1CYP1A2ABCG2TDP1L3MBTL1 | |
| SCHEMBL20205459 | 0.88 | GPR84 (0.38) | CYP1A1CYP1B1CYP1A2ABCG2HPGD | |
| SCHEMBL20205579 | 0.86 | TDP1 (0.34) | CYP1A1CYP1A2ABCG2KDM4ETDP1 | |
| SCHEMBL20205390 | 0.85 | PRKDC (0.36) | CYP1A1CYP1B1CYP1A2ABCC1ABCG2 | |
| SCHEMBL20205623 | 0.85 | PRKDC (0.34) | KDM4EMAPTHPGDALDH1A1PRKDC | |
| SCHEMBL20205622 | 0.85 | TDP1 (0.32) | CYP1A1CYP1A2ABCG2TDP1L3MBTL1 | |
| SCHEMBL20205631 | 0.84 | ALOX5 (0.36) | CYP1A2KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL20205375 | 0.84 | ENPP3 (0.36) | CYP2C9CYP2C19ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11453680-B2 | Bisbenzofuran-fused indeno[1,2-B]fluorene derivatives and related compounds as materials for organic electroluminescent devices (OLED) | MERCK PATENT GMBH (DE) | 2022-09-27 | — | — | US | disclosed |
| EP-3544985-B1 | BISBENZOFURAN-FUSED INDENO[1,2-B]FLUORENE DERIVATIVES AND RELATED COMPOUNDS AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES (OLED) | MERCK PATENT GMBH (DE) | 2021-05-12 | — | — | EP | disclosed |
| WO-2018095940-A1 | BISBENZOFURAN-FUSED INDENO[1,2-B]FLUORENE DERIVATIVES AND RELATED COMPOUNDS AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES (OLED) | MERCK PATENT GMBH (DE) | 2018-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11453680-B2 | Bisbenzofuran-fused indeno[1,2-B]fluorene derivatives and related compounds as materials for organic electroluminescent devices (OLED) | OCIAD2, OCIAD1, JUND | CYP1A1 366/4885CYP1B1 70/4885CYP1A2 356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.