Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24649647 | 0.96 | MAOA (0.32) | MAOAMAOBPGRGPR84ALOX5 | |
| SCHEMBL23351763 | 0.95 | MAOA (0.36) | MAOAMAOBPGRGPR84ALOX5 | |
| SCHEMBL20205469 | 0.95 | MAOA (0.36) | MAOAMAOBPGRGPR84ALOX5 | |
| SCHEMBL20205449 | 0.94 | ALOX5 (0.36) | MAOAMAOBPGRGPR84ALOX5 | |
| SCHEMBL20205630 | 0.94 | ALOX5 (0.36) | MAOAMAOBPGRGPR84ALOX5 | |
| SCHEMBL23351967 | 0.92 | ALOX5 (0.33) | MAOAMAOBPGRGPR84ALOX5 | |
| SCHEMBL20205312 | 0.90 | ENPP3 (0.34) | ALOX5 | |
| SCHEMBL24649901 | 0.87 | ALOX5 (0.36) | MAOAMAOBPGRALOX5TDP1 | |
| SCHEMBL20205321 | 0.87 | CDC14B (0.35) | PGRALOX5HPGDMAPTMEN1 | |
| SCHEMBL24649891 | 0.87 | CDC14B (0.37) | PGRHPGDMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3544985-B1 | BISBENZOFURAN-FUSED INDENO[1,2-B]FLUORENE DERIVATIVES AND RELATED COMPOUNDS AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES (OLED) | MERCK PATENT GMBH (DE) | 2021-05-12 | — | — | EP | disclosed |
| WO-2018095940-A1 | BISBENZOFURAN-FUSED INDENO[1,2-B]FLUORENE DERIVATIVES AND RELATED COMPOUNDS AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES (OLED) | MERCK PATENT GMBH (DE) | 2018-05-31 | — | — | WO | disclosed |