Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | KLK7 | P49862 | 1/20 | 0.46 |
| ▸ | KLK14 | Q9P0G3 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 2/20 | 0.45 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | PYGM | P11217 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2023578 | 0.88 | ABCG2 (0.49) | MEN1KMT2AKDRMAPT | |
| SCHEMBL2052134 | 0.85 | BRAF (0.49) | PTK2 | |
| SCHEMBL2020155 | 0.84 | ABCG2 (0.49) | MEN1KMT2AKDM1AMAPT | |
| SCHEMBL2023614 | 0.82 | RIPK1 (0.47) | MEN1KMT2ARXFP1RIPK1 | |
| SCHEMBL2023148 | 0.81 | MEN1 (0.44) | MEN1KMT2A | |
| SCHEMBL2028780 | 0.81 | MEN1 (0.38) | MEN1KMT2AKDRMAPT | |
| SCHEMBL2023155 | 0.81 | SYK (0.44) | KDM1AKDRPIK3CA | |
| SCHEMBL2026340 | 0.80 | ABCG2 (0.40) | PLK1 | |
| SCHEMBL2024076 | 0.80 | LIPG (0.41) | KDM1A | |
| SCHEMBL2030313 | 0.79 | MAPK8 (0.50) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011075747-A1 | THERAPEUTIC COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2011-06-23 | — | — | WO | disclosed |