⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20393742 | 0.86 | DDB1 (0.32) | — | |
| SCHEMBL21324910 | 0.77 | ALOX5 (0.33) | — | |
| SCHEMBL20206746 | 0.77 | CRBN (0.33) | — | |
| SCHEMBL22414473 | 0.75 | CRBN (0.35) | — | |
| SCHEMBL20374509 | 0.72 | CRBN (0.33) | — | |
| SCHEMBL24786715 | 0.69 | BRD4 (0.36) | — | |
| SCHEMBL21778450 | 0.68 | ALOX5 (0.39) | — | |
| SCHEMBL21524570 | 0.67 | PTGS1 (0.37) | — | |
| SCHEMBL19918750 | 0.67 | MITF (0.33) | — | |
| SCHEMBL22414503 | 0.67 | ALOX5 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098204-A1 | 6-MEMBERED URACIL ISOSTERES | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |