Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20201753 | 0.84 | ALOX5 (0.37) | ALDH1A1GAAGABRA1GABRG2GABRB3 | |
| SCHEMBL23367694 | 0.79 | CACNA1H (0.35) | GAAGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL20204735 | 0.78 | BRS3 (0.34) | — | |
| SCHEMBL4606408 | 0.74 | MMP2 (0.41) | ALDH1A1GAA | |
| SCHEMBL4606648 | 0.73 | MMP2 (0.52) | ALDH1A1GAAGABRA1GABRG2GABRB3 | |
| SCHEMBL2282179 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL4228688 | 0.65 | — | — | |
| SCHEMBL22871224 | 0.65 | TSHR (0.42) | ALDH1A1TSHR | |
| SCHEMBL25646251 | 0.64 | SYK (0.42) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL21325358 | 0.62 | BRS3 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098204-A1 | 6-MEMBERED URACIL ISOSTERES | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |