Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20206828 | 0.79 | ALDH1A1 (0.33) | SMPD3GAAGABRA1GABRG2GABRB3 | |
| SCHEMBL15893925 | 0.78 | CACNA1H (0.34) | CACNA1HMMP2HCAR2 | |
| SCHEMBL456 | 0.77 | BRS3 (0.38) | CACNA1HMMP2HCAR2HRH1 | |
| Hydrochloric Acid SCHEMBL8115870 | 0.76 | CACNA1H (0.33) | CACNA1HMMP2HCAR2HRH1 | |
| SCHEMBL14333827 | 0.74 | HCAR2 (0.34) | CACNA1HMMP2MAPTHCAR2POLB | |
| SCHEMBL21421720 | 0.72 | HRH1 (0.31) | MAPTHRH1HRH4POLB | |
| SCHEMBL14037700 | 0.72 | — | — | |
| SCHEMBL2282179 | 0.72 | — | — | |
| SCHEMBL20201753 | 0.69 | ALOX5 (0.37) | KDM4EGAAGABRA1GABRG2GABRB3 | |
| SCHEMBL22871224 | 0.68 | TSHR (0.42) | MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3190108-B1 | HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS | SAGIMET BIOSCIENCES INC (US) | 2021-05-19 | — | — | EP | disclosed |