Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPPA | P01160 | 2/20 | 0.38 |
| ▸ | MME | P08473 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27959576 | 0.80 | SORT1 (0.37) | NPPAMMECCNE2CCNE1CDK2 | |
| SCHEMBL13827902 | 0.77 | KDM4E (0.37) | ELANENOS3NOS1NOS2 | |
| SCHEMBL20207720 | 0.76 | NPPA (0.37) | NPPAMMEESR1NOS3NOS1 | |
| SCHEMBL12120806 | 0.75 | ELANE (0.34) | ELANE | |
| SCHEMBL24524637 | 0.75 | CCNE2 (0.32) | NPPAMMECCNE2CCNE1CDK2 | |
| SCHEMBL5541955 | 0.74 | — | — | |
| SCHEMBL2046063 | 0.74 | — | — | |
| SCHEMBL21325063 | 0.73 | NPPA (0.36) | NPPAMMEELANENOS3NOS1 | |
| SCHEMBL10271622 | 0.72 | ESR1 (0.30) | ESR1 | |
| SCHEMBL5535844 | 0.71 | CCNE2 (0.34) | NPPAMMECCNE2CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098204-A1 | 6-MEMBERED URACIL ISOSTERES | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |