Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPPA | P01160 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21325063 | 0.78 | NPPA (0.36) | NPPAMMENOS3NOS1NOS2 | |
| SCHEMBL20206958 | 0.76 | NPPA (0.38) | NPPAMMENOS3NOS1NOS2 | |
| SCHEMBL13171537 | 0.74 | NOS3 (0.41) | NPPAMMENOS3NOS1NOS2 | |
| SCHEMBL30142931 | 0.72 | NOS2 (0.44) | NPPAMMENOS3NOS1NOS2 | |
| SCHEMBL12120612 | 0.72 | NOS3 (0.36) | NPPAMMENOS3NOS1NOS2 | |
| SCHEMBL20153136 | 0.69 | — | — | |
| SCHEMBL1201329 | 0.66 | RORC (0.33) | NOS3NOS1NOS2KDM4EALDH1A1 | |
| SCHEMBL13827902 | 0.65 | KDM4E (0.37) | NOS3NOS1NOS2KDM4EHPGD | |
| SCHEMBL13827910 | 0.65 | NPPA (0.32) | NPPAMMENOS3NOS1NOS2 | |
| SCHEMBL20206847 | 0.64 | GABRA1 (0.38) | NOS3NOS1NOS2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098207-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |