SCHEMBL20207092

SCHEMBL20207092

CC(C)(C)OC(=O)/N=C(\NC(=O)OC(C)(C)C)Nc1ccc(OCCCNCCCCCCCCN/C(=N\C(=O)OC(C)(C)C)NC(=O)OC(C)(C)C)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.47
CA1 P00915 5/20 0.47
CA2 P00918 5/20 0.47
CA9 Q16790 5/20 0.47
KDM4E B2RXH2 1/20 0.41
MAPT P10636 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
SUCNR1 Q9BXA5 5/20 0.40
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
EPHX2 P34913 1/20 0.39
HDAC3 O15379 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC10 Q969S8 1/20 0.38
HDAC11 Q96DB2 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20204942 0.91 CA1 (0.45) CA12CA1CA2CA9KDM4E
SCHEMBL20207106 0.86 DRD2 (0.44) CA12CA1CA2CA9MAPT
SCHEMBL20207023 0.85 ALDH1A1 (0.42) CA12CA1CA2CA9EPHX2
SCHEMBL16808322 0.83 CA12 (0.47) CA12CA1CA2CA9KDM4E
SCHEMBL15149719 0.83 CA12 (0.42) CA12CA1CA2CA9ITGB3
SCHEMBL24671341 0.83 CA12 (0.49) CA12CA1CA2CA9KDM4E
SCHEMBL20207095 0.83 CA12 (0.39) CA12CA1CA2CA9EPHX2
SCHEMBL29802513 0.83 CA12 (0.51) CA12CA1CA2CA9SUCNR1
SCHEMBL24834412 0.83 CA12 (0.51) CA12CA1CA2CA9SUCNR1
SCHEMBL20204884 0.82 CA12 (0.38) CA12CA1CA2CA9KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018097126-A1 GUANIDINE COMPOUND AND FUNGICIDE 日本曹達株式会社 2018-05-31 WO disclosed