Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | LIPC | P11150 | 1/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20201444 | 0.90 | LIPC (0.38) | TP53L3MBTL1HTTTDP1POLB | |
| SCHEMBL24571585 | 0.82 | HRH2 (0.40) | L3MBTL1HTTLMNAALDH1A1HRH3 | |
| SCHEMBL14670935 | 0.82 | L3MBTL1 (0.47) | TP53L3MBTL1HTTTDP1LMNA | |
| SCHEMBL20201457 | 0.81 | GAA (0.42) | L3MBTL1LMNAALDH1A1TSHRMAPK1 | |
| SCHEMBL578343 | 0.81 | TP53 (0.46) | TP53L3MBTL1HTTLMNANPC1 | |
| SCHEMBL22592558 | 0.79 | TP53 (0.38) | TP53L3MBTL1HTTLMNANPC1 | |
| SCHEMBL24572108 | 0.78 | HRH2 (0.40) | ALDH1A1HRH3HRH2HRH1TSHR | |
| SCHEMBL771543 | 0.77 | TP53 (0.44) | TP53L3MBTL1HTTTDP1POLB | |
| SCHEMBL6603236 | 0.76 | GNAI3 (0.43) | TP53NPC1RAB9ACYP2D6HRH3 | |
| SCHEMBL6603242 | 0.76 | GNAI3 (0.43) | TP53NPC1RAB9ACYP2D6HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018128720-A1 | URACIL CONTAINING COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-07-12 | — | — | WO | disclosed |
| WO-2018098207-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |