Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18701282 | 0.83 | MAPT (0.39) | MAPTLMNAALDH1A1GRIA2GRIA4 | |
| SCHEMBL18701271 | 0.83 | ALDH1A1 (0.39) | LMNAALDH1A1PTGER1NPC1RAB9A | |
| SCHEMBL18701285 | 0.83 | MAPT (0.41) | MAPTLMNAGRIA2GRIA4PTGS1 | |
| SCHEMBL18701258 | 0.80 | ALDH1A1 (0.42) | MAPTLMNAALDH1A1PTGS2SMN1; SMN2 | |
| SCHEMBL12103427 | 0.75 | ALDH1A1 (0.42) | LMNAALDH1A1PTGER1NPC1RAB9A | |
| SCHEMBL18701256 | 0.75 | MAPT (0.45) | MAPTLMNAALDH1A1GRIA2GRIA4 | |
| SCHEMBL19663897 | 0.73 | GRIA4 (0.61) | LMNAGRIA2GRIA4SMN1; SMN2KMT2A | |
| SCHEMBL10949178 | 0.72 | MAOB (0.44) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6294085 | 0.71 | LMNA (0.48) | MAPTLMNAALDH1A1PTGS1PTGS2 | |
| SCHEMBL8618279 | 0.71 | LMNA (0.48) | MAPTLMNAALDH1A1PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180151807-A1 | ORGANIC COMPOSITION AND ELECTRONIC DEVICE COMPRISING ORGANIC LAYER COMPRISING SAID COMPOSITION | ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) | 2018-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180151807-A1 | ORGANIC COMPOSITION AND ELECTRONIC DEVICE COMPRISING ORGANIC LAYER COMPRISING SAID COMPOSITION | OR10J3, EPCAM, EPHA4 | MAPT 751/4885LMNA 1352/4885ALDH1A1 1950/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.