Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | CHUK | O15111 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | FABP4 | P15090 | 3/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.30 |
| ▸ | HTR2B | P41595 | 2/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20204869 | 0.83 | CHUK (0.34) | APPCHUKFABP4HTR2CHTR2B | |
| SCHEMBL21324920 | 0.80 | HTR2C (0.35) | APPCHUKCNR2FABP4HTR2C | |
| SCHEMBL20206774 | 0.76 | ADRA1A (0.38) | APPCHUKFABP4HTR2CHTR2B | |
| SCHEMBL20207787 | 0.76 | FABP4 (0.32) | CHUKCNR2FABP4HTR2CHTR2B | |
| SCHEMBL21324930 | 0.74 | FABP4 (0.35) | APPFABP4ALOX5APFEN1 | |
| SCHEMBL21324915 | 0.73 | HTR2C (0.34) | CNR2FABP4HTR2CHTR2B | |
| SCHEMBL21324921 | 0.73 | HTR2C (0.34) | CNR2FABP4HTR2CHTR2B | |
| SCHEMBL21533979 | 0.72 | HTR2C (0.33) | CNR2HTR2CHTR2B | |
| SCHEMBL21690527 | 0.72 | HTR2C (0.33) | CNR2FABP4HTR2CHTR2B | |
| SCHEMBL21533976 | 0.71 | HTR2C (0.33) | CNR2HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098207-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |