Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 3/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | CHUK | O15111 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21324930 | 0.92 | FABP4 (0.35) | ADRA1AACACBFABP4APPALOX5AP | |
| SCHEMBL20201618 | 0.84 | ALOX5AP (0.36) | ACACBHTR2CHTR7HTR2BHTR3A | |
| SCHEMBL20204868 | 0.82 | ADRA1A (0.40) | ADRA1AACACBFABP4HTR1AHTR1D | |
| SCHEMBL20207781 | 0.82 | ADRA1A (0.40) | ADRA1AACACBFABP4HTR1AHTR1D | |
| SCHEMBL21324931 | 0.78 | ADRA1A (0.38) | ADRA1AFABP4HTR2CHTR2BPDE4D | |
| SCHEMBL21324913 | 0.78 | ADRA1A (0.38) | ADRA1AFABP4HTR2CHTR2BPDE4D | |
| SCHEMBL20201600 | 0.77 | FABP4 (0.36) | ADRA1AACACBFABP4HTR2CPDE4D | |
| SCHEMBL21533978 | 0.76 | FEN1 (0.37) | ACACBALOX5APFEN1 | |
| SCHEMBL20207782 | 0.76 | APP (0.33) | FABP4APPHTR2CHTR2BPDE4D | |
| SCHEMBL20201595 | 0.76 | ADRA1A (0.35) | ADRA1AFABP4CHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098204-A1 | 6-MEMBERED URACIL ISOSTERES | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |