Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13327029 | 0.88 | DAO (0.41) | PARP1DAOKDM4EMAPTGABRA1 | |
| SCHEMBL2967282 | 0.80 | — | — | |
| SCHEMBL14012134 | 0.77 | GABRA1 (0.35) | PARP1DAOKDM4EGABRA1GABRB2 | |
| SCHEMBL20376636 | 0.77 | DAO (0.35) | PARP1DAOGABRA1GABRB2GPR84 | |
| SCHEMBL21324887 | 0.74 | DAO (0.33) | PARP1DAOKDM4EMAPTGPR84 | |
| SCHEMBL14754136 | 0.73 | — | — | |
| SCHEMBL20801759 | 0.73 | LOXL2 (0.33) | LOXL2 | |
| SCHEMBL9878781 | 0.69 | — | — | |
| SCHEMBL24881442 | 0.67 | PABPC1 (0.47) | PARP1DAOKDM4EGABRA1GABRB2 | |
| SCHEMBL14012135 | 0.67 | GABRA1 (0.35) | PARP1DAOGABRA1GABRB2GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098208-A1 | NITROGEN RING LINKED DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |