SCHEMBL20208610

SCHEMBL20208610

c1ccc(-c2ccccc2-c2ccc3c(c2)Oc2cc(-c4ccccc4-c4ccccc4)cc4c2N3c2cc3c5ccccc5n(-c5ccccc5)c3cc2O4)cc1

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
MAPK14 Q16539 1/20 0.31
KMT2A Q03164 1/20 0.30
IL1R1 P14778 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20208602 0.90 L3MBTL1 (0.41) KDM4EATML3MBTL1KMT2AIL1R1
SCHEMBL20208601 0.88 L3MBTL1 (0.39) KDM4EATML3MBTL1KMT2AIL1R1
SCHEMBL22958720 0.87 KDM4E (0.34) KDM4EATML3MBTL1MAPK14
SCHEMBL20209175 0.83 KDM4E (0.35) KDM4EATML3MBTL1KMT2AIL1R1
SCHEMBL20208726 0.81 KDM4E (0.41) KDM4EATML3MBTL1
SCHEMBL22958718 0.81 MGLL (0.34)
SCHEMBL22958792 0.81 L3MBTL1 (0.45) KDM4EATML3MBTL1KMT2AIL1R1
SCHEMBL22958706 0.81 L3MBTL1 (0.40) KDM4EATML3MBTL1KMT2AIL1R1
SCHEMBL25636733 0.81 L3MBTL1 (0.40) KDM4EATML3MBTL1KMT2AIL1R1
SCHEMBL22958756 0.80 L3MBTL1 (0.42) KDM4EATML3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3544986-B1 BRIDGED TRIARYLAMINES FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2020-12-23 EP disclosed
WO-2018095839-A1 BRIDGED TRIARYLAMINES FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2018-05-31 WO disclosed