SCHEMBL20209766

SCHEMBL20209766

Fc1cc(COc2c(F)cc(-c3ccc(C4OCCCO4)cc3)cc2F)cc(F)c1F

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 3/20 0.37
CYP11B2 P19099 3/20 0.37
FFAR4 Q5NUL3 10/20 0.37
F10 P00742 1/20 0.35
MAOB P27338 2/20 0.33
CCNB2 O95067 1/20 0.31
CDK1 P06493 1/20 0.31
CCNB1 P14635 1/20 0.31
GSK3B P49841 1/20 0.31
CDK5 Q00535 1/20 0.31
CDK5R1 Q15078 1/20 0.31
CCNB3 Q8WWL7 1/20 0.31
KDM1A O60341 2/20 0.30
MAOA P21397 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20209568 0.87 FFAR4 (0.33) CYP11B1CYP11B2FFAR4MAOB
SCHEMBL19098115 0.86 F10 (0.34) FFAR4F10MAOB
SCHEMBL20209635 0.85 PRKAG1 (0.40) FFAR4F10MAOB
SCHEMBL19850827 0.84 CYP11B1 (0.47) CYP11B1CYP11B2CCNB2CDK1CCNB1
SCHEMBL19082850 0.84 F10 (0.33) FFAR4F10MAOB
SCHEMBL17799306 0.82 FFAR4 (0.34) FFAR4F10MAOB
SCHEMBL17799308 0.82 FFAR4 (0.34) FFAR4F10MAOB
SCHEMBL19711842 0.81 FFAR4 (0.40) FFAR4F10MAOB
SCHEMBL19098114 0.80 F10 (0.33) FFAR4F10MAOBKDM1A
SCHEMBL19082863 0.80 FFAR4 (0.33) FFAR4F10MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200071617-A1 LIQUID CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2020-03-05 US disclosed
US-20190119575-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2019-04-25 US disclosed
US-20180148647-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY USING SAME DIC CORPORATION (JP) 2018-05-31 US disclosed