Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 16/20 | 0.54 |
| ▸ | AXL | P30530 | 5/20 | 0.47 |
| ▸ | KDR | P35968 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15519428 | 0.92 | MET (0.53) | METAXLKDR | |
| SCHEMBL3836125 | 0.90 | MET (0.50) | METAXL | |
| SCHEMBL3855044 | 0.89 | MET (0.55) | METKDR | |
| SCHEMBL2200943 | 0.83 | MET (0.53) | METKDR | |
| SCHEMBL3835125 | 0.82 | MET (0.49) | METAXLKDR | |
| SCHEMBL4413202 | 0.81 | MET (0.52) | METAXLKDR | |
| SCHEMBL4413214 | 0.81 | MET (0.47) | METKDR | |
| SCHEMBL4466096 | 0.81 | MET (0.51) | MET | |
| SCHEMBL3227275 | 0.80 | MET (0.53) | METKDR | |
| SCHEMBL3832618 | 0.80 | MET (0.52) | METKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3329918-A2 | C-MET MODULATORS AND METHODS OF USE | Exelixis, Inc. (US) | 2018-06-06 | — | — | EP | disclosed |