Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | NQO2 | P16083 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2549044 | 0.81 | ALDH1A1 (0.42) | ALDH1A1CYP3A4CYP1A2CA1CA2 | |
| SCHEMBL20212439 | 0.79 | CA1 (0.42) | ALDH1A1CYP3A4CA1CA2CA12 | |
| SCHEMBL180252 | 0.75 | ALDH1A1 (0.50) | ALDH1A1CYP3A4CYP1A2CA1CA2 | |
| SCHEMBL25053617 | 0.73 | CA12 (0.52) | ALDH1A1CYP3A4CYP1A2CA1CA2 | |
| Bromide SCHEMBL20424457 | 0.73 | ALDH1A1 (0.48) | ALDH1A1CYP3A4CYP1A2CA1CA2 | |
| SCHEMBL31325535 | 0.73 | ALDH1A1 (0.48) | ALDH1A1CYP3A4CYP1A2CA1CA2 | |
| SCHEMBL2886444 | 0.71 | ALDH1A1 (0.46) | ALDH1A1CYP3A4CYP1A2CA1CA2 | |
| SCHEMBL5358569 | 0.71 | ALDH1A1 (0.46) | ALDH1A1CYP3A4CYP1A2CA1CA2 | |
| SCHEMBL6754210 | 0.71 | ALDH1A1 (0.46) | ALDH1A1CYP3A4CYP1A2CA1CA2 | |
| SCHEMBL2551364 | 0.71 | CA1 (0.36) | ALDH1A1CYP3A4CYP1A2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10544177-B2 | Chiral dihydrobenzooxaphosphole ligands and synthesis thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2020-01-28 | — | — | US | disclosed |
| EP-3551638-A2 | NOVEL CHIRAL DIHYDROBENZOOXAPHOSPHOLE LIGANDS AND SYNTHESIS THEREOF | Boehringer Ingelheim International GmbH (DE) | 2019-10-16 | — | — | EP | disclosed |
| US-20190144475-A1 | NOVEL CHIRAL DIHYDROBENZOOXAPHOSPHOLE LIGANDS AND SYNTHESIS THEREOF | BOEHRINGER INGELHEIM INT (DE) | 2019-05-16 | — | — | US | disclosed |
| US-10221203-B2 | Chiral dihydrobenzooxaphosphole ligands and synthesis thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2019-03-05 | — | — | US | disclosed |
| WO-2018106746-A2 | NOVEL CHIRAL DIHYDROBENZOOXAPHOSPHOLE LIGANDS AND SYNTHESIS THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2018-06-14 | — | — | WO | disclosed |
| US-20180155375-A1 | NOVEL CHIRAL DIHYDROBENZOOXAPHOSPHOLE LIGANDS AND SYNTHESIS THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2018-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190144475-A1 | NOVEL CHIRAL DIHYDROBENZOOXAPHOSPHOLE LIGANDS AND SYNTHESIS THEREOF | DCPS, PPIP5K2, PNPO | ALDH1A1 2050/4885CYP3A4 1314/4885CYP1A2 2896/4885 |
| US-10544177-B2 | Chiral dihydrobenzooxaphosphole ligands and synthesis thereof | DCPS, PNPO, PPIP5K2 | ALDH1A1 2152/4885CYP3A4 1241/4885CYP1A2 2559/4885 |
| US-10221203-B2 | Chiral dihydrobenzooxaphosphole ligands and synthesis thereof | DCPS, PNPO, PPIP5K2 | ALDH1A1 2152/4885CYP3A4 1241/4885CYP1A2 2559/4885 |
| US-20180155375-A1 | NOVEL CHIRAL DIHYDROBENZOOXAPHOSPHOLE LIGANDS AND SYNTHESIS THEREOF | DCPS, PPIP5K2, PNPO | ALDH1A1 2050/4885CYP3A4 1314/4885CYP1A2 2896/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.