Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.46 |
| ▸ | HTR3B | O95264 | 2/20 | 0.46 |
| ▸ | HTR3A | P46098 | 2/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | PMM2 | O15305 | 1/20 | 0.34 |
| ▸ | MPI | P34949 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21377608 | 0.84 | MAPK1 (0.48) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL20213932 | 0.84 | HTR3E (0.48) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL29435789 | 0.72 | PGR (0.39) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL21377498 | 0.72 | PGR (0.39) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL30396176 | 0.68 | MAPK1 (0.58) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL12116179 | 0.68 | MAPK1 (0.58) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL31576798 | 0.67 | MAPK1 (0.62) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL29375842 | 0.67 | MAPK1 (0.62) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL8759349 | 0.67 | MAPK1 (0.62) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL9129351 | 0.67 | MAPK1 (0.62) | HTR3EHTR3BHTR3AHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11254702-B2 | Thionyl tetrafluoride modified compounds and uses | THE SCRIPPS RESEARCH INSTITUTE (US) | 2022-02-22 | — | — | US | disclosed |
| EP-3548465-A1 | THIONYL TETRAFLUORIDE MODIFIED COMPOUNDS AND USES | The Scripps Research Institute (US) | 2019-10-09 | — | — | EP | disclosed |
| US-20190284226-A1 | THIONYL TETRAFLUORIDE MODIFIED COMPOUNDS AND USES | THE SCRIPPS RESEARCH INSTITUTE | 2019-09-19 | — | — | US | disclosed |
| WO-2018102433-A1 | THIONYL TETRAFLUORIDE MODIFIED COMPOUNDS AND USES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2018-06-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190284226-A1 | THIONYL TETRAFLUORIDE MODIFIED COMPOUNDS AND USES | SFXN3, TST, SIRT3 | HTR3E 298/4885HTR3B 568/4885HTR3A 205/4885 |
| US-11254702-B2 | Thionyl tetrafluoride modified compounds and uses | SFXN3, TST, SIRT3 | HTR3E 298/4885HTR3B 568/4885HTR3A 205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.