Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | BCL2 | P10415 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25766398 | 0.93 | DNM1 (0.50) | DNM1ALDH1A1TSHRLMNAHTR1A | |
| SCHEMBL27424910 | 0.84 | DNM1 (0.38) | DNM1ALDH1A1TSHRHTR1ADRD2 | |
| SCHEMBL12394800 | 0.82 | ALDH1A1 (0.43) | DNM1ALDH1A1TSHRLMNABCL2 | |
| SCHEMBL23902959 | 0.80 | DNM1 (0.46) | DNM1ALDH1A1TSHRLMNABCL2 | |
| SCHEMBL23192219 | 0.80 | DNM1 (0.46) | DNM1ALDH1A1TSHRHTR1ADRD2 | |
| SCHEMBL19669297 | 0.79 | CYP2C19 (0.47) | DNM1ALDH1A1TSHRSIGMAR1 | |
| SCHEMBL24383549 | 0.78 | MAPT (0.43) | DNM1ALDH1A1TSHRLMNABCL2 | |
| SCHEMBL19853473 | 0.78 | — | — | |
| SCHEMBL23902941 | 0.76 | DNM1 (0.48) | DNM1ALDH1A1TSHRLMNABCL2 | |
| SCHEMBL19448671 | 0.76 | DNM1 (0.42) | DNM1ALDH1A1TSHRLMNABCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230055682-A1 | SYNTHETIC GUIDE RNA, COMPOSITIONS, METHODS, AND USES THEREOF | BEAM THERAPEUTICS INC. | 2023-02-23 | — | — | US | disclosed |
| US-9988386-B2 | Compounds for treatment of diseases of abnormal angiogenesis or aberrant growth factors and uses thereof | Kata Pharmaceuticals, Inc. (US) | 2018-06-05 | — | — | US | disclosed |