Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | BCL2 | P10415 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22986016 | 0.78 | CES2 (0.33) | TSHRLMNA | |
| SCHEMBL18482581 | 0.77 | — | — | |
| SCHEMBL23902959 | 0.76 | DNM1 (0.46) | DNM1ALDH1A1TSHRLMNABCL2 | |
| SCHEMBL20214874 | 0.76 | DNM1 (0.46) | DNM1ALDH1A1TSHRLMNABCL2 | |
| SCHEMBL24716317 | 0.75 | ALDH1A1 (0.45) | DNM1ALDH1A1TSHRLMNABCL2 | |
| SCHEMBL7849144 | 0.73 | CES2 (0.45) | TSHR | |
| SCHEMBL13453389 | 0.73 | CES2 (0.45) | TSHR | |
| SCHEMBL20653333 | 0.73 | — | — | |
| SCHEMBL14532686 | 0.73 | CES2 (0.45) | TSHR | |
| SCHEMBL14479235 | 0.73 | CES2 (0.45) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017174621-A1 | PYRIDYL DERIVATIVES AS BROMODOMAIN INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2017-10-12 | — | — | WO | disclosed |