SCHEMBL20214935

SCHEMBL20214935

CC(C)NC(=O)CCSC(C)C

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HPGD P15428 5/20 0.50
MEN1 O00255 1/20 0.48
FAAH O00519 1/20 0.48
MAPK1 P28482 1/20 0.48
KMT2A Q03164 1/20 0.48
MAPT P10636 1/20 0.40
ALDH1A1 P00352 2/20 0.39
LMNA P02545 1/20 0.37
TSHR P16473 1/20 0.37
CHRM5 P08912 1/20 0.35
CHRM3 P20309 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
SDCBP O00560 2/20 0.33
SDC2 P34741 2/20 0.33
POLB P06746 1/20 0.33
METAP2 P50579 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
NLRP1 Q9C000 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6536861 0.82 LMNA (0.56) HPGDMEN1FAAHMAPK1KMT2A
SCHEMBL12448086 0.80 HPGD (0.51) HPGDMEN1FAAHMAPK1KMT2A
SCHEMBL13241285 0.79 HPGD (0.44) HPGDMEN1FAAHMAPK1KMT2A
SCHEMBL25083266 0.78 HPGD (0.50) HPGDMEN1FAAHMAPK1KMT2A
SCHEMBL5909062 0.78 MEN1 (0.62) HPGDMEN1FAAHMAPK1KMT2A
SCHEMBL17661831 0.77 MAPK1 (0.44) HPGDMEN1FAAHMAPK1KMT2A
SCHEMBL21972899 0.77 MEN1 (0.52) HPGDMEN1FAAHMAPK1KMT2A
SCHEMBL22916866 0.77 FAAH (0.45) HPGDFAAHKMT2AMAPTALDH1A1
SCHEMBL12132164 0.76 CPB1 (0.45) HPGDMEN1FAAHMAPK1KMT2A
SCHEMBL18857492 0.75 HPGD (0.47) HPGDMEN1FAAHMAPK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240238439-A1 HER3-BINDING ANTIBODY-DRUG CONJUGATE Hummingbird Bioscience Pte. Ltd. (SG) 2024-07-18 US disclosed
WO-2021216572-A1 LIPID COMPOSITIONS FOR DELIVERY OF STING AGONIST COMPOUNDS AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2021-10-28 WO disclosed
US-9988420-B2 Cytotoxic peptides and conjugates thereof NOVARTIS AG (CH) 2018-06-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240238439-A1 HER3-BINDING ANTIBODY-DRUG CONJUGATE ERBB3, EGFR, ERBB2 HPGD 4682/4885MEN1 557/4885FAAH 3925/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.