Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12541530 | 0.91 | ALDH1A1 (0.59) | ALDH1A1HPGDCYP3A4MAPK1MAPT | |
| SCHEMBL1282546 | 0.88 | ALDH1A1 (0.62) | ALDH1A1HPGDCYP3A4MAPK1KMT2A | |
| SCHEMBL20215153 | 0.87 | TP53 (0.48) | ALDH1A1HPGDCYP3A4MAPK1MAPT | |
| SCHEMBL20445972 | 0.87 | KMT2A (0.57) | ALDH1A1HPGDCYP3A4MAPK1MAPT | |
| SCHEMBL1546520 | 0.87 | TP53 (0.51) | ALDH1A1HPGDCYP3A4MAPK1MAPT | |
| SCHEMBL20204164 | 0.87 | TP53 (0.48) | ALDH1A1HPGDCYP3A4MAPK1MAPT | |
| SCHEMBL13019654 | 0.86 | MAPT (0.55) | ALDH1A1HPGDCYP3A4MAPK1MAPT | |
| Peonol Methyl Ether SCHEMBL29402500 | 0.85 | ALDH1A1 (0.67) | ALDH1A1HPGDCYP3A4MAPK1MAPT | |
| Peonol Methyl Ether SCHEMBL246262 | 0.85 | ALDH1A1 (0.67) | ALDH1A1HPGDCYP3A4MAPK1MAPT | |
| Peonol Methyl Ether SCHEMBL4700333 | 0.85 | ALDH1A1 (0.67) | ALDH1A1HPGDCYP3A4MAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10329279-B2 | Chiral synthesis method for producing cis-imidazoline compounds for pharmaceutical use | UNITY BIOTECHNOLOGY, INC. (US) | 2019-06-25 | — | — | US | disclosed |
| US-9988368-B1 | Chiral synthesis method for producing cis-imidazoline compounds for pharmaceutical use | UNITY BIOTECHNOLOGY, INC. (US) | 2018-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10329279-B2 | Chiral synthesis method for producing cis-imidazoline compounds for pharmaceutical use | MDM2, CDKN1A, TP53 | ALDH1A1 2863/4885HPGD 1717/4885CYP3A4 171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.