Peonol Methyl Ether

Peonol Methyl Ether

SCHEMBL4700333

COc1ccc(C(C)=O)c(OC)c1.COc1ccc(C(C)=O)c(OC)c1

nearest known ligand 0.67

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.67
HPGD P15428 3/20 0.67
CYP3A4 P08684 2/20 0.67
MAPK1 P28482 1/20 0.67
KMT2A Q03164 4/20 0.66
NPC1 O15118 2/20 0.66
MAPT P10636 4/20 0.65
RAD52 P43351 1/20 0.59
MEN1 O00255 3/20 0.59
CYP1A2 P05177 2/20 0.59
CYP2C19 P33261 2/20 0.59
RAB9A P51151 2/20 0.59
ABCG2 Q9UNQ0 2/20 0.58
TNFRSF1A P19438 1/20 0.57
GAA P10253 1/20 0.56
LMNA P02545 2/20 0.55
PDE4A P27815 1/20 0.55
PDE4B Q07343 1/20 0.55
PDE4C Q08493 1/20 0.55
PDE4D Q08499 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Peonol Methyl Ether SCHEMBL29402500 1.00 ALDH1A1 (0.67) ALDH1A1HPGDCYP3A4MAPK1KMT2A
Peonol Methyl Ether SCHEMBL246262 1.00 ALDH1A1 (0.67) ALDH1A1HPGDCYP3A4MAPK1KMT2A
SCHEMBL18758273 0.87 KMT2A (0.53) ALDH1A1HPGDCYP3A4MAPK1KMT2A
SCHEMBL285924 0.86 NPC1 (0.79) ALDH1A1HPGDCYP3A4KMT2ANPC1
SCHEMBL31575666 0.86 NPC1 (0.79) ALDH1A1HPGDCYP3A4KMT2ANPC1
SCHEMBL20215988 0.85 ALDH1A1 (0.59) ALDH1A1HPGDCYP3A4MAPK1KMT2A
SCHEMBL7497130 0.85 KDM4E (0.61) ALDH1A1HPGDCYP3A4MAPK1KMT2A
SCHEMBL28350600 0.85 ALDH1A1 (0.54) ALDH1A1HPGDCYP3A4MAPK1KMT2A
SCHEMBL29581343 0.84 MAPT (0.68) ALDH1A1HPGDCYP3A4MAPK1KMT2A
SCHEMBL885028 0.84 MAPT (0.68) ALDH1A1HPGDCYP3A4MAPK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1602354-B1 Use of polyglutamic acid or its salts MEIJI SEIKA KAISHA (JP) 2008-11-05 EP disclosed
US-20060165636-A1 Hair treatment composition and hair cosmetic for damaged hair MEIJI SEIKA KAISHA, LTD. (JP) 2006-07-27 US disclosed
EP-1602354-A1 HAIR TREATMENT COMPOSITION AND HAIR COSMETIC FOR DAMAGED HAIR Meiji Seika Kaisha, Ltd. (JP) 2005-12-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060165636-A1 Hair treatment composition and hair cosmetic for damaged hair CUTA, COL14A1, PRKDC ALDH1A1 2963/4885HPGD 3285/4885CYP3A4 4880/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.