Peonol Methyl Ether

Peonol Methyl Ether

SCHEMBL246262

COc1ccc(C(C)=O)c(OC)c1

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.67
HPGD P15428 3/20 0.67
CYP3A4 P08684 2/20 0.67
MAPK1 P28482 1/20 0.67
KMT2A Q03164 4/20 0.66
NPC1 O15118 2/20 0.66
MAPT P10636 4/20 0.65
RAD52 P43351 1/20 0.59
MEN1 O00255 3/20 0.59
CYP1A2 P05177 2/20 0.59
CYP2C19 P33261 2/20 0.59
RAB9A P51151 2/20 0.59
ABCG2 Q9UNQ0 2/20 0.58
TNFRSF1A P19438 1/20 0.57
GAA P10253 1/20 0.56
LMNA P02545 2/20 0.55
PDE4A P27815 1/20 0.55
PDE4B Q07343 1/20 0.55
PDE4C Q08493 1/20 0.55
PDE4D Q08499 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Peonol Methyl Ether SCHEMBL4700333 1.00 ALDH1A1 (0.67) ALDH1A1HPGDCYP3A4MAPK1KMT2A
Peonol Methyl Ether SCHEMBL29402500 1.00 ALDH1A1 (0.67) ALDH1A1HPGDCYP3A4MAPK1KMT2A
SCHEMBL18758273 0.87 KMT2A (0.53) ALDH1A1HPGDCYP3A4MAPK1KMT2A
SCHEMBL285924 0.86 NPC1 (0.79) ALDH1A1HPGDCYP3A4KMT2ANPC1
SCHEMBL31575666 0.86 NPC1 (0.79) ALDH1A1HPGDCYP3A4KMT2ANPC1
SCHEMBL20215988 0.85 ALDH1A1 (0.59) ALDH1A1HPGDCYP3A4MAPK1KMT2A
SCHEMBL7497130 0.85 KDM4E (0.61) ALDH1A1HPGDCYP3A4MAPK1KMT2A
SCHEMBL28350600 0.85 ALDH1A1 (0.54) ALDH1A1HPGDCYP3A4MAPK1KMT2A
SCHEMBL29581343 0.84 MAPT (0.68) ALDH1A1HPGDCYP3A4MAPK1KMT2A
SCHEMBL885028 0.84 MAPT (0.68) ALDH1A1HPGDCYP3A4MAPK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 486 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116924993-A Preparation method of 1-cyclopentyl-3- (2, 4-dimethoxy phenyl) -2-oxo ethyl) imidazolidine-2, 4, 5-trione 川北医学院 2023-10-24 CN claimed
CN-115960480-A Light response self-repairing material containing thymine derivative and application thereof 合肥工业大学 2023-04-14 CN claimed
CN-114146071-B Application of paeonol and its derivatives in preventing and treating leukoplakia syndrome 西北农林科技大学深圳研究院 2023-02-28 CN claimed
CN-114146071-A Application of paeonol and its derivatives in preventing and treating leukoplakia syndrome 西北农林科技大学深圳研究院 2022-03-08 CN claimed
CN-112778208-A Dihydropyrazole MurA enzyme inhibitor molecule and preparation method and application thereof 中南民族大学 2021-05-11 CN claimed
EP-2906529-B9 A NEW PRODUCTION METHOD AND NEW INTERMEDIATES OF SYNTHESIS OF ELVITEGRAVIR ZENTIVA KS (CZ) 2017-03-15 EP claimed
EP-2906529-B1 A NEW PRODUCTION METHOD AND NEW INTERMEDIATES OF SYNTHESIS OF ELVITEGRAVIR ZENTIVA KS (CZ) 2016-11-23 EP claimed
CN-105907342-A Silicone sealant for aluminum-sheet curtain wall 烟台图文马克化工科技有限公司 2016-08-31 CN claimed
CN-104447556-B A kind of compound with analgesic activity and preparation method thereof SOUTH-CENTRAL UNIVERSITY FOR NATIONALITIES (CN) 2016-05-18 CN claimed
CN-105237037-A Water-proofing agent for natural stone building YANTAI SHUNLONG CHEMICAL ENGINEERING TECHNOLOGY CO LTD 2016-01-13 CN claimed
US-6410795-B1 FORMING DIKETONES CROMPTON CORPORATION 2002-06-25 US claimed
EP-1208371-A1 DISPOSABLE THERMOFORMED ELECTROPHORESIS CASSETTE Mirador DNA Design Inc. (CA) 2002-05-29 EP claimed
EP-1192141-A1 1,4-DIAZACYCLOHEPTANE DERIVATIVES AS NEUROPROTECTIVE AGENTS AstraZeneca UK Limited (GB) 2002-04-03 EP claimed
EP-1140863-A1 1,4-DIAZACYCLOHEPTANE DERIVATIVES USEFUL IN THE TREATMENT OF NEUROLOGICAL DISORDERS AstraZeneca AB (SE) 2001-10-10 EP claimed
WO-2001016589-A1 DISPOSABLE THERMOFORMED ELECTROPHORESIS CASSETTE MIRADOR DNA DESIGN INC. (CA) 2001-03-08 WO claimed
WO-2000078736-A1 1,4-DIAZACYCLOHEPTANE DERIVATIVES AS NEUROPROTECTIVE AGENTS ASTRAZENECA UK LIMITED (GB) 2000-12-28 WO claimed
WO-2000039105-A1 1,4-DIAZACYCLOHEPTANE DERIVATIVES USEFUL IN THE TREATMENT OF NEUROLOGICAL DISORDERS ASTRAZENECA AB (SE) 2000-07-06 WO claimed
EP-0674233-B1 Recording sheets XEROX CORP (US) 2000-05-24 EP claimed
US-5928765-A Recording sheets XEROX CORPORATION (US) 1999-07-27 US claimed
EP-0674233-A2 Recording sheets XEROX CORPORATION (US) 1995-09-27 EP claimed