Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 5/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 4/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18086330 | 0.91 | TERT (0.39) | TERTKDM4EMTNR1APPARGNR1H2 | |
| SCHEMBL22404704 | 0.91 | TERT (0.40) | TERTMTNR1APPARGNR1H2NR1H3 | |
| SCHEMBL22172455 | 0.91 | TERT (0.40) | TERTHIF1AMTNR1APPARGNR1H2 | |
| SCHEMBL20375671 | 0.91 | MTNR1A (0.36) | TERTCA12CA1CA2CA3 | |
| SCHEMBL22077955 | 0.90 | HPGD (0.42) | CA12CA1CA2CA3CA4 | |
| SCHEMBL17954246 | 0.89 | TERT (0.37) | TERTMTNR1APPARGNR1H2NR1H3 | |
| SCHEMBL17955294 | 0.89 | TERT (0.39) | TERTPPARGNR1H2NR1H3PPARD | |
| SCHEMBL17381242 | 0.88 | CA12 (0.41) | CA12CA1CA2CA3CA4 | |
| SCHEMBL17954278 | 0.88 | GAA (0.34) | TERTCA12CA1CA2CA3 | |
| SCHEMBL20101483 | 0.88 | CA12 (0.36) | TERTCA12CA1CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9988627-B2 | Formats for organic compounds for use in RNA interference | NOVARTIS AG (CH) | 2018-06-05 | — | — | US | disclosed |