Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 10/20 | 0.63 |
| ▸ | CTSK | P43235 | 9/20 | 0.63 |
| ▸ | CTSB | P07858 | 4/20 | 0.63 |
| ▸ | CTSL | P07711 | 2/20 | 0.63 |
| ▸ | AKT1 | P31749 | 1/20 | 0.55 |
| ▸ | ACE | P12821 | 1/20 | 0.55 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.51 |
| ▸ | REN | P00797 | 1/20 | 0.51 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.51 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.51 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.51 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.51 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20030538 | 1.00 | CTSS (0.63) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL31364171 | 0.98 | CTSS (0.60) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL16983230 | 0.98 | CTSS (0.60) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL24094584 | 0.98 | CTSS (0.60) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL6047666 | 0.98 | CTSS (0.60) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL30692461 | 0.92 | REN (0.64) | CTSSCTSKCTSBCTSLREN | |
| SCHEMBL22300786 | 0.92 | REN (0.64) | CTSSCTSKCTSBCTSLREN | |
| SCHEMBL2793925 | 0.90 | CTSS (0.76) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL1001781 | 0.90 | CTSS (0.76) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL31364169 | 0.90 | CTSS (0.59) | CTSSCTSKCTSBCTSLAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119176852-A | Preparation method of amino acid with protection tetrapeptide | 四川鸿日医药科技有限公司 | 2024-12-24 | — | — | CN | disclosed |
| CN-115960111-A | Antibody-drug conjugates | 第一三共株式会社 | 2023-04-14 | — | — | CN | disclosed |
| US-9988408-B2 | Cytotoxic agents for conjugation to a cell binding molecule | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2018-06-05 | — | — | US | disclosed |