Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 10/20 | 0.60 |
| ▸ | CTSK | P43235 | 9/20 | 0.60 |
| ▸ | CTSB | P07858 | 4/20 | 0.60 |
| ▸ | CTSL | P07711 | 2/20 | 0.60 |
| ▸ | AKT1 | P31749 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 1/20 | 0.53 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.49 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.49 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.49 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.49 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.49 |
| ▸ | REN | P00797 | 1/20 | 0.49 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6047666 | 1.00 | CTSS (0.60) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL16983230 | 1.00 | CTSS (0.60) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL31364171 | 1.00 | CTSS (0.60) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL20216484 | 0.98 | CTSS (0.63) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL20030538 | 0.98 | CTSS (0.63) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL31364169 | 0.92 | CTSS (0.59) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL21320235 | 0.92 | CTSS (0.59) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL18429365 | 0.92 | CTSS (0.62) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL18495335 | 0.92 | CTSS (0.62) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL27371144 | 0.91 | CTSS (0.58) | CTSSCTSKCTSBCTSLAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210386866-A1 | ANTIBODY-DRUG CONJUGATES CONTAINING AN ANTI-MESOTHELIN ANTIBODY AND USES THEREOF | DEVELOPMENT CENTER FOR BIOTECHNOLOGY (TW) | 2021-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210386866-A1 | ANTIBODY-DRUG CONJUGATES CONTAINING AN ANTI-MESOTHELIN ANTIBODY AND USES THEREOF | MUC1, EPCAM, CD44 | CTSS 2945/4885CTSK 2582/4885CTSB 1627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.