Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | F3 | P13726 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.39 |
| ▸ | CLK2 | P49760 | 3/20 | 0.39 |
| ▸ | CLK3 | P49761 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 5/20 | 0.37 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20217257 | 0.89 | F10 (0.41) | F10F2PRSS1PRSS2F7 | |
| SCHEMBL20217559 | 0.88 | OPRK1 (0.36) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL20217585 | 0.85 | HRH3 (0.38) | HRH3 | |
| SCHEMBL20217160 | 0.85 | CHEK2 (0.41) | F10F2PRSS1PRSS2F7 | |
| SCHEMBL20217405 | 0.79 | MAPT (0.44) | F10KDRSMN1; SMN2LCK | |
| SCHEMBL20217430 | 0.78 | F10 (0.42) | F10F2PRSS1PRSS2F7 | |
| SCHEMBL20217692 | 0.77 | KDR (0.38) | F10F2PRSS1PRSS2F7 | |
| SCHEMBL20217305 | 0.76 | HSD17B10 (0.49) | F10 | |
| SCHEMBL20217334 | 0.76 | ALDH1A1 (0.50) | F10F2PRSS1PRSS2F7 | |
| SCHEMBL20217272 | 0.76 | KDM4E (0.49) | F2PRSS1HRH3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2766352-B1 | INDAZOLE COMPOUNDS AS KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIV HEALTH NETWORK UHN (CA) | 2018-06-06 | — | — | EP | disclosed |