Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 6/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2022004 | 0.70 | CNR1 (0.55) | RORCKDM4E | |
| SCHEMBL2909582 | 0.53 | RAB9A (0.57) | SMN1; SMN2MEN1KMT2ASMYD3HPGD | |
| SCHEMBL19662207 | 0.52 | BRD4 (0.72) | BRD4 | |
| SCHEMBL4478521 | 0.52 | HDAC8 (0.60) | SMN1; SMN2BRD4ALDH1A1HTTTSHR | |
| SCHEMBL24784223 | 0.52 | HPGD (0.53) | SMN1; SMN2BRD4MEN1KMT2ASMYD3 | |
| SCHEMBL10528098 | 0.52 | EPHX2 (0.47) | MEN1KMT2ALMNAALDH1A1TSHR | |
| SCHEMBL10527634 | 0.52 | LMNA (0.51) | SMN1; SMN2MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL20674093 | 0.52 | BRD4 (0.44) | CYP3A4CYP2D6CYP2C9BRD4MEN1 | |
| SCHEMBL12084650 | 0.52 | NPC1 (0.58) | SMN1; SMN2MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL20812406 | 0.52 | HPGD (0.68) | MEN1KMT2AALDH1A1TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110160180-A1 | Cannabinoid Receptor Ligands | ASTRAZENECA AB (SE) | 2011-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160180-A1 | Cannabinoid Receptor Ligands | CNR1, CNR2, OPRL1 | RORC 574/4885SMN1; SMN2 1384/4885CYP3A4 1129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.