SCHEMBL20220123

SCHEMBL20220123

Oc1ccc(-c2cc(-c3ccccc3)cc(-c3ccccc3)n2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.71
KMT2A Q03164 5/20 0.71
NTSR1 P30989 1/20 0.71
MMP3 P08254 1/20 0.62
BCL2L1 Q07817 1/20 0.62
POLB P06746 2/20 0.59
ALDH1A1 P00352 1/20 0.59
MAPT P10636 1/20 0.59
HPGD P15428 1/20 0.59
HSD17B10 Q99714 1/20 0.59
ESR1 P03372 6/20 0.57
ESR2 Q92731 4/20 0.57
CDC7 O00311 1/20 0.56
CYP19A1 P11511 1/20 0.53
MCL1 Q07820 1/20 0.51
PIM1 P11309 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
ADORA1 P30542 1/20 0.51
CTRC Q99895 1/20 0.50
ABL1 P00519 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22538001 1.00 MEN1 (0.71) MEN1KMT2ANTSR1MMP3BCL2L1
SCHEMBL30901160 1.00 MEN1 (0.71) MEN1KMT2ANTSR1MMP3BCL2L1
Hydroquinone SCHEMBL16236259 0.98 MEN1 (0.68) MEN1KMT2ANTSR1MMP3BCL2L1
SCHEMBL27860886 0.91 ALDH1A1 (0.62) MEN1KMT2ANTSR1MMP3BCL2L1
SCHEMBL4404689 0.89 CYP19A1 (0.63) MEN1KMT2ANTSR1ALDH1A1MAPT
SCHEMBL10051450 0.89 CYP19A1 (0.63) MEN1KMT2ANTSR1ALDH1A1MAPT
SCHEMBL12258341 0.89 CYP19A1 (0.63) MEN1KMT2ANTSR1ALDH1A1MAPT
SCHEMBL19860206 0.89 CYP19A1 (0.63) MEN1KMT2ANTSR1ALDH1A1MAPT
SCHEMBL10051447 0.89 CYP19A1 (0.63) MEN1KMT2ANTSR1ALDH1A1MAPT
SCHEMBL10051444 0.89 CYP19A1 (0.63) MEN1KMT2ANTSR1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11730009-B2 Compound and organic light-emitting element comprising same LG CHEM, LTD. 2023-08-15 US disclosed
US-11730009-B2 Compound and organic light-emitting element comprising same LG CHEM, LTD. 2023-08-15 US disclosed
EP-3330265-B1 COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2020-04-15 EP disclosed
EP-3330265-A1 COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG Chem, Ltd. (KR) 2018-06-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11730009-B2 Compound and organic light-emitting element comprising same CRY2, CRY1, NR2E3 MEN1 673/4885KMT2A 551/4885NTSR1 4796/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.