Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16370114 | 1.00 | CHRNB2 (0.41) | CHRNB2CHRNA5CHRNA7CHRNA4MEN1 | |
| SCHEMBL16370113 | 1.00 | CHRNB2 (0.41) | CHRNB2CHRNA5CHRNA7CHRNA4MEN1 | |
| SCHEMBL16370388 | 0.85 | LMNA (0.42) | CHRNB2CHRNA5CHRNA7CHRNA4KMT2A | |
| SCHEMBL16370390 | 0.85 | LMNA (0.42) | CHRNB2CHRNA5CHRNA7CHRNA4KMT2A | |
| SCHEMBL18573967 | 0.82 | LMNA (0.44) | CHRNB2CHRNA5CHRNA7CHRNA4MEN1 | |
| SCHEMBL15106358 | 0.78 | ALDH1A1 (0.40) | CHRNB2CHRNA5CHRNA7CHRNA4MEN1 | |
| SCHEMBL15106356 | 0.78 | ALDH1A1 (0.40) | CHRNB2CHRNA5CHRNA7CHRNA4MEN1 | |
| SCHEMBL21082360 | 0.77 | LMNA (0.45) | CHRNB2CHRNA5CHRNA7CHRNA4MEN1 | |
| SCHEMBL16369934 | 0.77 | LMNA (0.39) | CHRNB2CHRNA5CHRNA7CHRNA4KMT2A | |
| SCHEMBL16369933 | 0.77 | LMNA (0.39) | CHRNB2CHRNA5CHRNA7CHRNA4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3019196-B1 | COMBINATIONS OF HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-06-06 | — | — | EP | disclosed |