Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8984274 | 0.88 | APEX1 (0.55) | ALDH1A1APEX1TDP1LMNAKMT2A | |
| SCHEMBL8984339 | 0.84 | APEX1 (0.46) | ALDH1A1APEX1TDP1LMNAKMT2A | |
| SCHEMBL23531323 | 0.81 | APEX1 (0.48) | ALDH1A1APEX1TDP1LMNAKMT2A | |
| SCHEMBL19658289 | 0.80 | APEX1 (0.42) | ALDH1A1APEX1TDP1LMNAKMT2A | |
| SCHEMBL13901852 | 0.79 | APEX1 (0.46) | ALDH1A1APEX1TDP1LMNAKMT2A | |
| SCHEMBL7131000 | 0.78 | APEX1 (0.74) | ALDH1A1APEX1TDP1LMNAKMT2A | |
| SCHEMBL22598062 | 0.77 | PAOX (0.44) | ALDH1A1APEX1LMNAKMT2AHTT | |
| SCHEMBL11246621 | 0.76 | APEX1 (0.42) | APEX1LMNAKMT2APOLBCES2 | |
| SCHEMBL9626977 | 0.76 | TSHR (0.50) | ALDH1A1APEX1LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL10583773 | 0.76 | APEX1 (0.70) | ALDH1A1APEX1TDP1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180154018-A1 | PEPTIDE-CONTAINING LINKERS FOR ANTIBODY-DRUG CONJUGATES | MERSANA THERAPEUTICS, INC. | 2018-06-07 | — | — | US | disclosed |
| US-9012398-B2 | Acylated exendin-4 compounds | NOVO NORDISK A/S (DK) | 2015-04-21 | — | — | US | disclosed |
| US-8835379-B2 | Derivatives of CGRP | NOVO NORDISK A/S (DK) | 2014-09-16 | — | — | US | disclosed |
| US-8536122-B2 | Acylated GLP-1 compounds | NOVO NORDISK A/S (DK) | 2013-09-17 | — | — | US | disclosed |
| US-20120295847-A1 | Acylated GLP-1 Compounds | NOVO NORDISK A/S (DK) | 2012-11-22 | — | — | US | disclosed |
| US-20120283170-A1 | Acylated Exendin-4 Compounds | NOVO NORDISK A/S (DK) | 2012-11-08 | — | — | US | disclosed |
| US-20120245083-A1 | Derivatives of CGRP | NOVO NORDISK A/S (DK) | 2012-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295847-A1 | Acylated GLP-1 Compounds | GLP1R, GIPR, GCGR | ALDH1A1 1380/4885APEX1 2434/4885TDP1 3207/4885 |
| US-20120283170-A1 | Acylated Exendin-4 Compounds | GLP1R, VIP, IAPP | ALDH1A1 4133/4885APEX1 3233/4885TDP1 4516/4885 |
| US-20120245083-A1 | Derivatives of CGRP | CALCB, CALCA, CALCRL | ALDH1A1 1201/4885APEX1 3485/4885TDP1 3102/4885 |
| US-20180154018-A1 | PEPTIDE-CONTAINING LINKERS FOR ANTIBODY-DRUG CONJUGATES | CD2BP2, DNPEP, LNPEP | ALDH1A1 3141/4885APEX1 1213/4885TDP1 2169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.