Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.72 |
| ▸ | EGFR | P00533 | 5/20 | 0.69 |
| ▸ | TEC | P42680 | 4/20 | 0.68 |
| ▸ | BMX | P51813 | 4/20 | 0.68 |
| ▸ | LYN | P07948 | 4/20 | 0.68 |
| ▸ | ITK | Q08881 | 3/20 | 0.68 |
| ▸ | LCK | P06239 | 3/20 | 0.68 |
| ▸ | BLK | P51451 | 3/20 | 0.68 |
| ▸ | TXK | P42681 | 2/20 | 0.68 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.68 |
| ▸ | NUDT14 | O95848 | 2/20 | 0.68 |
| ▸ | NUDT5 | Q9UKK9 | 2/20 | 0.68 |
| ▸ | ABL1 | P00519 | 2/20 | 0.68 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.68 |
| ▸ | FYN | P06241 | 2/20 | 0.68 |
| ▸ | YES1 | P07947 | 2/20 | 0.68 |
| ▸ | HCK | P08631 | 2/20 | 0.68 |
| ▸ | FGR | P09769 | 2/20 | 0.68 |
| ▸ | SRC | P12931 | 2/20 | 0.68 |
| ▸ | FER | P16591 | 2/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18493108 | 0.95 | BTK (0.73) | BTKEGFRTECBMXLYN | |
| SCHEMBL21398244 | 0.95 | BTK (0.73) | BTKEGFRTECBMXLYN | |
| SCHEMBL25069063 | 0.88 | BTK (0.75) | BTKEGFRLYNITKLCK | |
| SCHEMBL19519589 | 0.85 | BTK (0.71) | BTKEGFRTECBMXLYN | |
| SCHEMBL19176281 | 0.85 | BTK (0.62) | BTKEGFRTECBMXLYN | |
| SCHEMBL200392 | 0.84 | BTK (1.00) | BTKEGFRTECBMXLYN | |
| SCHEMBL201548 | 0.84 | BTK (1.00) | BTKEGFRTECBMXLYN | |
| SCHEMBL200391 | 0.84 | BTK (1.00) | BTKEGFRTECBMXLYN | |
| SCHEMBL24827785 | 0.84 | BTK (0.80) | BTKEGFRTECBMXLYN | |
| SCHEMBL22002211 | 0.83 | BTK (0.71) | BTKEGFRTECBMXLYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10226466-B2 | Methods of treating fibrosis | PHARMACYCLICS LLC (US) | 2019-03-12 | — | — | US | disclosed |
| US-20180153896-A1 | METHODS OF TREATING FIBROSIS | PHARMACYCLICS LLC | 2018-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10226466-B2 | Methods of treating fibrosis | MYLK, MMP1, MMP8 | BTK 18/4885EGFR 1613/4885TEC 813/4885 |
| US-20180153896-A1 | METHODS OF TREATING FIBROSIS | MYLK, MMP1, MMP8 | BTK 18/4885EGFR 1613/4885TEC 813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.