SCHEMBL2022470

SCHEMBL2022470

Cc1cc(Cl)ccc1-c1cccc(COc2ccc(CO)c(F)c2)c1

nearest known ligand 0.53

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 19/20 0.53
FFAR4 Q5NUL3 1/20 0.53
MAOB P27338 1/20 0.48
PPARD Q03181 5/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2022259 0.82 FFAR1 (0.52) FFAR1FFAR4MAOBPPARD
SCHEMBL2024484 0.82 MAOB (0.58) FFAR1MAOBPPARD
SCHEMBL12578548 0.79 FFAR1 (0.66) FFAR1FFAR4MAOBPPARD
SCHEMBL28485471 0.78 MAOB (0.55) FFAR1FFAR4MAOB
SCHEMBL2025724 0.77 FFAR1 (0.58) FFAR1FFAR4MAOB
SCHEMBL12577930 0.76 FFAR1 (0.55) FFAR1FFAR4MAOB
SCHEMBL2023225 0.76 FFAR1 (0.47) FFAR1
SCHEMBL2027506 0.76 FFAR1 (0.59) FFAR1FFAR4MAOB
SCHEMBL23004608 0.75 MAOB (0.61) MAOB
SCHEMBL30398602 0.75 MAOB (0.61) MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7968552-B2 Oxadiazolidinedione compound ASTELLAS PHARMA INC. (JP) 2011-06-28 US disclosed
US-20090186909-A1 Oxadiazolidinedione Compound ASTELLAS PHARMA INC. (JP) 2009-07-23 US disclosed
EP-2011788-A1 OXADIAZOLIDINEDIONE COMPOUND Astellas Pharma Inc. (JP) 2009-01-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090186909-A1 Oxadiazolidinedione Compound GPR119, GPR39, GPR65 FFAR1 64/4885FFAR4 54/4885MAOB 3965/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.