Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALB | P02768 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | POLG | P54098 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20224848 | 0.93 | STING1 (0.35) | STING1ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL20224989 | 0.85 | STING1 (0.34) | STING1ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL22990446 | 0.84 | STING1 (0.34) | STING1ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL22990440 | 0.84 | STING1 (0.34) | STING1ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL20224845 | 0.84 | TYMS (0.42) | — | |
| SCHEMBL21362282 | 0.83 | ALDH1A1 (0.44) | ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL20224899 | 0.82 | ALDH1A1 (0.45) | STING1ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL20224907 | 0.82 | ALDH1A1 (0.45) | STING1ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL20224887 | 0.75 | TYMS (0.42) | — | |
| SCHEMBL20224901 | 0.75 | ALDH1A1 (0.45) | ALDH1A1LMNAALBMAPK1POLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512861-B1 | CYCLIC DINUCLEOTIDES AS STING (STIMULATOR OF INTERFERON GENES) AGONISTS | TAKEDA PHARMACEUTICALS CO (JP) | 2021-02-17 | — | — | EP | disclosed |
| WO-2018100558-A2 | CYCLIC DINUCLEOTIDE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-06-07 | — | — | WO | disclosed |