Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TYMP | P19971 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21362217 | 0.92 | ALDH1A1 (0.46) | ALDH1A1LMNAALBMAPK1TYMP | |
| SCHEMBL21133324 | 0.84 | ALDH1A1 (0.38) | ALDH1A1LMNAALBMAPK1TYMP | |
| SCHEMBL20224847 | 0.83 | STING1 (0.33) | ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL21132765 | 0.82 | ALDH1A1 (0.38) | ALDH1A1LMNAALBMAPK1TYMP | |
| SCHEMBL21417395 | 0.82 | ALDH1A1 (0.69) | ALDH1A1LMNAALBMAPK1TYMP | |
| SCHEMBL21132949 | 0.82 | ALDH1A1 (0.69) | ALDH1A1LMNAALBMAPK1TYMP | |
| SCHEMBL21362298 | 0.82 | ALDH1A1 (0.64) | ALDH1A1LMNAALBMAPK1TYMP | |
| SCHEMBL26558586 | 0.81 | ALDH1A1 (0.40) | ALDH1A1LMNAALBMAPK1TYMP | |
| SCHEMBL22219806 | 0.81 | TAS1R3 (0.54) | ALDH1A1LMNAALBMAPK1P2RY1 | |
| SCHEMBL22352200 | 0.81 | POLB (0.53) | ALDH1A1BCHEP2RY1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3765474-B1 | CYCLOPENTANE-BASED MODULATORS OF STING (STIMULATOR OF INTERFERON GENES) | PFIZER (US) | 2022-06-15 | — | — | EP | disclosed |
| WO-2019175776-A1 | CYCLOPENTANE-BASED MODULATORS OF STING (STIMULATOR OF INTERFERON GENES) | PFIZER INC. (US) | 2019-09-19 | — | — | WO | disclosed |