⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL202623 | 0.74 | — | — | |
| SCHEMBL191733 | 0.64 | HTR2A (0.33) | — | |
| SCHEMBL5124109 | 0.61 | TP53 (0.32) | — | |
| SCHEMBL4056836 | 0.60 | TLR7 (0.40) | — | |
| SCHEMBL10123166 | 0.59 | POLB (0.37) | — | |
| SCHEMBL204000 | 0.55 | KDM4E (0.39) | — | |
| SCHEMBL1933022 | 0.52 | HTT (0.46) | — | |
| SCHEMBL12457543 | 0.52 | ALDH1A1 (0.46) | — | |
| SCHEMBL1104755 | 0.51 | KDM4E (0.51) | — | |
| SCHEMBL5894528 | 0.51 | KDM4E (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088788-B2 | Substituted fused[1,2] imidazo[4,5-c] ring compounds and methods | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-01-03 | — | — | US | disclosed |
| US-20090221551-A1 | SUBSTITUTED FUSED[1,2] IMIDAZO[4,5C] RING COMPOUNDS AND METHODS | PFIZER INC. | 2009-09-03 | — | — | US | disclosed |
| WO-2007106852-A2 | SUBSTITUTED FUSED[1,2]IMIDAZO[4,5-C] RING COMPOUNDS AND METHODS | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2007-09-20 | — | — | WO | disclosed |