Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL247478 | 0.72 | ALDH1A1 (0.41) | KDM4EMAPTALDH1A1ERN1NPC1 | |
| SCHEMBL29364156 | 0.72 | ALDH1A1 (0.41) | KDM4EMAPTALDH1A1ERN1NPC1 | |
| SCHEMBL1933022 | 0.70 | HTT (0.46) | KDM4EMAPTALDH1A1ERN1NPC1 | |
| SCHEMBL12457543 | 0.70 | ALDH1A1 (0.46) | KDM4EMAPTALDH1A1NPC1POLB | |
| SCHEMBL5894537 | 0.69 | ALDH1A1 (0.43) | KDM4EMAPTALDH1A1ERN1NPC1 | |
| SCHEMBL5894144 | 0.69 | MMP2 (0.35) | KDM4EMAPTALDH1A1NPC1POLB | |
| SCHEMBL195792 | 0.67 | ATM (0.43) | NPC1RAB9A | |
| SCHEMBL2078225 | 0.67 | ALDH1A1 (0.50) | KDM4EMAPTALDH1A1NPC1POLB | |
| SCHEMBL240893 | 0.65 | ALDH1A1 (0.38) | KDM4EMAPTALDH1A1 | |
| Bromide SCHEMBL7758538 | 0.64 | ALDH1A1 (0.37) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060156485-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060156485-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | KRT18, TUBB6, DNMT1 | KDM4E 571/4885MAPT 1322/4885ALDH1A1 385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.