Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20224969 | 0.84 | TBXAS1 (0.60) | MAPK1ALDH1A1L3MBTL1KMT2ALMNA | |
| SCHEMBL20224953 | 0.84 | POLB (0.52) | MAPK1ALDH1A1L3MBTL1CASP1KMT2A | |
| SCHEMBL14368556 | 0.83 | TDP1 (0.61) | MAPK1ALDH1A1L3MBTL1CASP1KMT2A | |
| SCHEMBL20224971 | 0.80 | MAPK1 (0.50) | MAPK1ALDH1A1L3MBTL1CASP1KMT2A | |
| SCHEMBL19007852 | 0.79 | ALDH1A1 (0.59) | MAPK1ALDH1A1L3MBTL1CASP1LMNA | |
| SCHEMBL20224965 | 0.78 | L3MBTL1 (0.51) | MAPK1ALDH1A1L3MBTL1CASP1KMT2A | |
| SCHEMBL3963428 | 0.78 | ALDH1A1 (0.68) | MAPK1ALDH1A1L3MBTL1KMT2ALMNA | |
| SCHEMBL18673 | 0.78 | ALDH1A1 (0.68) | MAPK1ALDH1A1L3MBTL1KMT2ALMNA | |
| SCHEMBL14793821 | 0.78 | TRPV1 (0.57) | MAPK1ALDH1A1L3MBTL1CASP1LMNA | |
| SCHEMBL19007857 | 0.77 | MAPT (0.62) | MAPK1ALDH1A1L3MBTL1TDP1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180154332-A1 | HIGH PURITY CHROMATOGRAPHIC MATERIALS COMPRISING ION PAIRED-BONDED PHASES FOR SUPERCRITICAL FLUID CHROMATOGRAPHY | WATERS TECHNOLOGIES CORPORATION | 2018-06-07 | — | — | US | disclosed |