Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium SCHEMBL7545662 | 0.98 | SIGMAR1 (0.43) | TSHRSIGMAR1CHRM2HTR1AADRA2A | |
| Potassium SCHEMBL7551769 | 0.98 | SIGMAR1 (0.43) | TSHRSIGMAR1CHRM2HTR1AADRA2A | |
| Methane SCHEMBL5909544 | 0.98 | SIGMAR1 (0.43) | TSHRSIGMAR1CHRM2HTR1AADRA2A | |
| SCHEMBL7621701 | 0.84 | TSHR (0.52) | TSHRSIGMAR1MAOACES1HPGD | |
| SCHEMBL11591007 | 0.84 | MAOA (0.55) | MAOAACHECES1BCHEL3MBTL1 | |
| SCHEMBL31392285 | 0.83 | SIGMAR1 (0.39) | TSHRSIGMAR1CHRM2HTR1AADRA2A | |
| SCHEMBL8662164 | 0.83 | CES1 (0.46) | TSHRSIGMAR1MAOACES1HPGD | |
| SCHEMBL13120272 | 0.80 | MAOA (0.55) | MAOAACHECES1BCHEL3MBTL1 | |
| SCHEMBL110502 | 0.80 | CES1 (0.48) | TSHRSIGMAR1MAOACES1HPGD | |
| SCHEMBL536818 | 0.80 | TSHR (0.52) | TSHRSIGMAR1MAOACES1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 278 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11939456-B2 | Composition for preparing a foam, foam, and shoe employing the same | TSRC CORPORATION (TW) | 2024-03-26 | — | — | US | claimed |
| CN-117736374-A | Cyclic olefin composition and application thereof | 杭州睿丰融创科技有限公司 | 2024-03-22 | — | — | CN | claimed |
| CN-117417512-A | Cyclic olefin ring-opening polymer hydride for medical instrument and preparation method thereof | 杭州睿丰融创科技有限公司 | 2024-01-19 | — | — | CN | claimed |
| CN-107735451-B | Resin composition, resin molded article, and optical member | 日本瑞翁株式会社 | 2022-12-27 | — | — | CN | claimed |
| CN-112867728-A | Copper chelated (pyridylmethylene) butanediamine derivatives | 冷泉港实验室 | 2021-05-28 | — | — | CN | claimed |
| EP-3823977-A1 | (PYRIDINYLMETHYL)BUTANEDIAMINE DERIVATIVES THAT CHELATE COPPER | Cold Spring Harbor Laboratory (US) | 2021-05-26 | — | — | EP | claimed |
| WO-2020018893-A1 | (PYRIDINYLMETHYL)BUTANEDIAMINE DERIVATIVES THAT CHELATE COPPER | COLD SPRING HARBOR LABORATORY (US) | 2020-01-23 | — | — | WO | claimed |
| CN-109280255-A | Composition for preparing foam, foam and shoe body containing foam | 台橡股份有限公司 | 2019-01-29 | — | — | CN | claimed |
| US-20190023884-A1 | COMPOSITION FOR PREPARING A FOAM, FOAM, AND SHOE EMPLOYING THE SAME | TSRC CORPORATION (TW) | 2019-01-24 | — | — | US | claimed |
| EP-3431544-A1 | COMPOSITION FOR PREPARING A FOAM, FOAM, AND SHOE EMPLOYING THE SAME | TSRC Corporation (TW) | 2019-01-23 | — | — | EP | claimed |
| EP-1006134-B1 | NORBORNENE POLYMER AND PROCESS FOR THE PREPARATION THEREOF | NIPPON ZEON CO (JP) | 2003-10-15 | — | — | EP | claimed |
| US-6525144-B1 | Heat resistant, nondeforming molding materials | NIPPON ZEON CO., LTD. (JP) | 2003-02-25 | — | — | US | claimed |
| EP-0900228-B1 | A METHOD FOR PRODUCING OCTAHYDROFLUORENYL METAL COMPLEXES | DOW CHEMICAL CO (US) | 2002-06-12 | — | — | EP | claimed |
| US-6344585-B2 | DEHYDROGENATION OF THE CORRESPONDING TETRAHYDROFLUORENECOMPOUND | ADCHEMCO CORPORATION (JP) | 2002-02-05 | — | — | US | claimed |
| US-20010011144-A1 | Preparation process of fluorenes | ADCHEMCO CORPORATION (JP) | 2001-08-02 | — | — | US | claimed |
| EP-1120389-A1 | Preparation process of fluorenes | Adchemco Corporation (JP) | 2001-08-01 | — | — | EP | claimed |
| EP-1006134-A1 | NORBORNENE POLYMER AND PROCESS FOR THE PREPARATION THEREOF | NIPPON ZEON CO., LTD. (JP) | 2000-06-07 | — | — | EP | claimed |
| EP-0900228-A1 | A METHOD FOR PRODUCING OCTAHYDROFLUORENYL METAL COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 1999-03-10 | — | — | EP | claimed |
| WO-1997041134-A1 | A METHOD FOR PRODUCING OCTAHYDROFLUORENYL METAL COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 1997-11-06 | — | — | WO | claimed |
| US-5670680-A | Method for producing octahydrofluorenyl metal complexes | THE DOW CHEMICAL COMPANY (US) | 1997-09-23 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010011144-A1 | Preparation process of fluorenes | AFF1, NAF1, RER1 | TSHR 775/4885SIGMAR1 470/4885CHRM2 2866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.