Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 2/20 | 0.48 |
| ▸ | MMP2 | P08253 | 2/20 | 0.48 |
| ▸ | MMP9 | P14780 | 2/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5435241 | 0.82 | MAOA (0.51) | MAOAMAOBPTGS1PTGS2ALOX5 | |
| SCHEMBL5599097 | 0.82 | CYP1A2 (0.61) | MAOAMAOBPTGS1PTGS2ALOX5 | |
| SCHEMBL5599099 | 0.82 | CYP1A2 (0.61) | MAOAMAOBPTGS1PTGS2ALOX5 | |
| SCHEMBL14924400 | 0.81 | MAOA (0.50) | MAOAMAOBPTGS1PTGS2ALOX5 | |
| SCHEMBL6603490 | 0.80 | TDP1 (0.62) | MAOAMAOBPTGS1PTGS2ALOX5 | |
| SCHEMBL79074 | 0.80 | NPSR1 (0.62) | MAOAMAOBHDAC3HDAC4HDAC1 | |
| SCHEMBL9714866 | 0.80 | NPSR1 (0.62) | MAOAMAOBHDAC3HDAC4HDAC1 | |
| SCHEMBL79073 | 0.80 | NPSR1 (0.62) | MAOAMAOBHDAC3HDAC4HDAC1 | |
| SCHEMBL8948080 | 0.80 | TDP1 (0.62) | MAOAMAOBPTGS1PTGS2ALOX5 | |
| SCHEMBL29426419 | 0.80 | NPSR1 (0.62) | MAOAMAOBHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018100191-A1 | AGROCHEMICAL COMPOSITIONS COMPRISING PHENYL-PROPANOIC ACID DERIVATIVES FOR CROP YIELD INCREASE | VIB VZW (BE) | 2018-06-07 | — | — | WO | disclosed |