Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.62 |
| ▸ | MAOA | P21397 | 2/20 | 0.59 |
| ▸ | MAOB | P27338 | 2/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.55 |
| ▸ | IAPP | P10997 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | FBP1 | P09467 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 3/20 | 0.51 |
| ▸ | MMP2 | P08253 | 3/20 | 0.51 |
| ▸ | MMP9 | P14780 | 3/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6603490 | 1.00 | TDP1 (0.62) | TDP1GLAMAOAMAOBPTGS1 | |
| SCHEMBL14441060 | 0.88 | GLA (0.72) | TDP1GLAPTGS1IAPPMAPT | |
| SCHEMBL5599097 | 0.86 | CYP1A2 (0.61) | TDP1MAOAMAOBPTGS1ALOX5 | |
| SCHEMBL5599099 | 0.86 | CYP1A2 (0.61) | TDP1MAOAMAOBPTGS1ALOX5 | |
| SCHEMBL79073 | 0.85 | NPSR1 (0.62) | TDP1GLAMAOAMAOBPTGS1 | |
| SCHEMBL79074 | 0.85 | NPSR1 (0.62) | TDP1GLAMAOAMAOBPTGS1 | |
| SCHEMBL9714866 | 0.85 | NPSR1 (0.62) | TDP1GLAMAOAMAOBPTGS1 | |
| SCHEMBL29426419 | 0.85 | NPSR1 (0.62) | TDP1GLAMAOAMAOBPTGS1 | |
| SCHEMBL31202444 | 0.83 | MAOA (0.62) | TDP1MAOAMAOBPTGS1ALOX5 | |
| SCHEMBL6752531 | 0.83 | MAOA (0.62) | TDP1MAOAMAOBPTGS1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110713436-B | Method for carrying out 1, 4-conjugated reduction by photochemical catalysis of alpha, beta-ketene compound | 北京工商大学 | 2022-06-14 | — | — | CN | claimed |
| EP-4727923-A1 | TETRAHYDROACRIDINONE ANALOGUES FOR TREATMENT AND PREVENTION OF MALARIA | University of Georgia Research Foundation, Inc. (US) | 2026-04-22 | — | — | EP | disclosed |
| US-20260098012-A1 | TETRAHYDROACRIDINONE ANALOGUES FOR TREATMENT AND PREVENTION OF MALARIA | UNIV GEORGIA (US) | 2026-04-09 | — | — | US | disclosed |
| WO-2024258904-A1 | TETRAHYDROACRIDINONE ANALOGUES FOR TREATMENT AND PREVENTION OF MALARIA | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2024-12-19 | — | — | WO | disclosed |
| CN-115232019-A | Synthetic method of 3-acetamido benzotrifluoride compound | 闽江学院 | 2022-10-25 | — | — | CN | disclosed |
| CN-110713436-B | Method for carrying out 1, 4-conjugated reduction by photochemical catalysis of alpha, beta-ketene compound | 北京工商大学 | 2022-06-14 | — | — | CN | disclosed |
| CN-112266352-B | Piperlongumine derivative and preparation method and application thereof | 绍兴文理学院 | 2022-02-08 | — | — | CN | disclosed |
| CN-112266352-A | Piperlongumine derivative and preparation method and application thereof | 绍兴文理学院 | 2021-01-26 | — | — | CN | disclosed |
| WO-2020210662-A1 | SMALL MOLECULES FOR CANCER THERAPY THAT REDUCE THE EXPRESSION OF TRANSCRIPTION FACTORS KLF5 AND EGR-1 | THE SCRIPPS RESEARCH INSTITUTE (US) | 2020-10-15 | — | — | WO | disclosed |
| CN-110713436-A | Method for carrying out 1, 4-conjugated reduction by photochemical catalysis of alpha, beta-ketene compound | 北京工商大学 | 2020-01-21 | — | — | CN | disclosed |
| US-9399701-B2 | Polymer compositions and methods | NOVOMER, INC. (US) | 2016-07-26 | — | — | US | disclosed |
| WO-2015106292-A1 | BCR-ABL TYROSINE-KINASE LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | COFERON, INC. (US) | 2015-07-16 | — | — | WO | disclosed |
| WO-2015081280-A1 | BROMODOMAIN LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION | COFERON, INC. (US) | 2015-06-04 | — | — | WO | disclosed |
| US-8491973-B2 | Photo-alignment material and liquid crystal display device and its manufacturing method using the same | LG DISPLAY CO., LTD. (KR) | 2013-07-23 | — | — | US | disclosed |
| EP-1997501-A2 | Extracts from Ajuga reptans cell lines, their preparation and use | I.R.B. Istituto Di Ricerche Biotecnologiche S.r.l. (IT) | 2008-12-03 | — | — | EP | disclosed |
| US-5484949-A | Method for the synthesis of α β-unsaturated ketones | NIPPON SODA CO., LTD. (JP) | 1996-01-16 | — | — | US | disclosed |
| EP-0454867-A1 | A METHOD FOR THE SYNTHESIS OF -g(a), -g(b)-UNSATURATED KETONES. | NIPPON SODA CO (JP) | 1991-11-06 | — | — | EP | disclosed |
| WO-1991007370-A1 | A METHOD FOR THE SYNTHESIS OF α, β-UNSATURATED KETONES | NIPPON SODA CO., LTD. (JP) | 1991-05-30 | — | — | WO | disclosed |
| US-3989708-A | HYPOTENSIVE, CORONARY VESSEL DILATORS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260098012-A1 | TETRAHYDROACRIDINONE ANALOGUES FOR TREATMENT AND PREVENTION OF MALARIA | CD47, SLC11A2, G6PD | TDP1 4043/4885GLA 4412/4885MAOA 4393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.