Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7145405 | 1.00 | HSD17B10 (0.39) | HSD17B10ATMNR1H2CYP1A2POLB | |
| SCHEMBL27732779 | 0.87 | HSD17B10 (0.41) | HSD17B10NR1H2CYP1A2POLBCYP3A4 | |
| SCHEMBL701488 | 0.86 | MMP2 (0.42) | HSD17B10NR1H2CYP1A2POLBCYP3A4 | |
| SCHEMBL5062575 | 0.86 | MMP2 (0.42) | HSD17B10NR1H2CYP1A2POLBCYP3A4 | |
| SCHEMBL7141767 | 0.86 | MMP2 (0.42) | HSD17B10NR1H2CYP1A2POLBCYP3A4 | |
| SCHEMBL5062574 | 0.86 | MMP2 (0.42) | HSD17B10NR1H2CYP1A2POLBCYP3A4 | |
| SCHEMBL19432138 | 0.85 | HSD17B10 (0.41) | HSD17B10ATMNR1H2CYP1A2POLB | |
| SCHEMBL6122248 | 0.85 | HSD17B10 (0.41) | HSD17B10ATMNR1H2CYP1A2POLB | |
| SCHEMBL6122243 | 0.85 | HSD17B10 (0.41) | HSD17B10ATMNR1H2CYP1A2POLB | |
| SCHEMBL8806575 | 0.82 | NR1H2 (0.38) | HSD17B10NR1H2CYP1A2POLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118791495-B | Carbapenem antibiotic and preparation method thereof | 青松(天津)制药有限公司 | 2024-11-26 | — | — | CN | disclosed |
| CN-118791495-A | Carbapenem antibiotic and preparation method thereof | 青松(天津)制药有限公司 | 2024-10-18 | — | — | CN | disclosed |
| EP-2177522-B1 | NOVEL CARBAPENEM DERIVATIVES | XUANZHU PHARMA CO LTD (CN) | 2013-09-04 | — | — | EP | disclosed |
| US-8318716-B2 | Carbapenem derivatives | KBP BIOSCIENCES CO., LTD. (CN) | 2012-11-27 | — | — | US | disclosed |
| US-8293895-B2 | Carbapenem derivatives | KBP BIOSCIENCES CO., LTD. (CN) | 2012-10-23 | — | — | US | disclosed |
| US-8293895-B2 | Carbapenem derivatives | KBP BIOSCIENCES CO., LTD. (CN) | 2012-10-23 | — | — | US | disclosed |
| US-20110160177-A1 | NOVEL CARBAPENEM DERIVATIVES | XUANZHU (HAINAN) BIOPHARMACEUTICAL CO., LTD. (CN) | 2011-06-30 | — | — | US | disclosed |
| US-20100197653-A1 | NOVEL CARBAPENEM DERIVATIVES | KBP BIOSCIENCES CO., LTD. (CN) | 2010-08-05 | — | — | US | disclosed |
| US-20100197653-A1 | NOVEL CARBAPENEM DERIVATIVES | KBP BIOSCIENCES CO., LTD. (CN) | 2010-08-05 | — | — | US | disclosed |
| CN-101720326-A | Novel carbapenem derivatives | KBP BIOSCIENCES CO LTD | 2010-06-02 | — | — | CN | disclosed |
| EP-2177522-A1 | NOVEL CARBAPENEM DERIVATIVES | KBP Biosciences Co., Ltd. (CN) | 2010-04-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160177-A1 | NOVEL CARBAPENEM DERIVATIVES | MGAM, RPIA, MGAM2 | HSD17B10 258/4885ATM 2950/4885NR1H2 586/4885 |
| US-20100197653-A1 | NOVEL CARBAPENEM DERIVATIVES | SI, MGAM, IDE | HSD17B10 174/4885ATM 2496/4885NR1H2 634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.