Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 13/20 | 0.48 |
| ▸ | LIPG | Q9Y5X9 | 13/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | LAP3 | P28838 | 1/20 | 0.35 |
| ▸ | P4HB | P07237 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29507270 | 1.00 | LPL (0.48) | LPLLIPGP2RX7ANPEPLAP3 | |
| SCHEMBL29470922 | 0.89 | LPL (0.41) | LPLLIPG | |
| SCHEMBL29470928 | 0.89 | LPL (0.41) | LPLLIPGP4HBPRMT5WDR77 | |
| SCHEMBL18492678 | 0.89 | LIPG (0.53) | LPLLIPGANPEPLAP3P4HB | |
| SCHEMBL25257161 | 0.89 | LPL (0.41) | LPLLIPGP4HBPRMT5WDR77 | |
| SCHEMBL24254101 | 0.89 | ALDH1A1 (0.46) | LPLLIPGANPEPLAP3PRMT5 | |
| SCHEMBL31624089 | 0.89 | LIPG (0.53) | LPLLIPGANPEPLAP3P4HB | |
| SCHEMBL25226735 | 0.89 | LPL (0.41) | LPLLIPG | |
| SCHEMBL31690690 | 0.89 | LPL (0.41) | LPLLIPGPRMT5WDR77CA1 | |
| SCHEMBL5899734 | 0.88 | LPL (0.54) | LPLLIPGP2RX7ANPEPLAP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3548481-B1 | HETEROCYCLIC COMPOUNDS FOR USE IN ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-08-23 | — | — | EP | disclosed |
| EP-3548481-B1 | HETEROCYCLIC COMPOUNDS FOR USE IN ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-08-23 | — | — | EP | disclosed |
| US-11329233-B2 | Heterocyclic compounds for use in electronic devices | MERCK PATENT GMBH (DE) | 2022-05-10 | — | — | US | disclosed |
| US-11329233-B2 | Heterocyclic compounds for use in electronic devices | MERCK PATENT GMBH (DE) | 2022-05-10 | — | — | US | disclosed |
| US-20190296250-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2019-09-26 | — | — | US | disclosed |
| US-20190296250-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2019-09-26 | — | — | US | disclosed |
| WO-2018100029-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-06-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190296250-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN ELECTRONIC DEVICES | NQO1, DDT, ETV6 | LPL 4846/4885LIPG 4202/4885P2RX7 254/4885 |
| US-11329233-B2 | Heterocyclic compounds for use in electronic devices | NQO1, DDT, ETV6 | LPL 4846/4885LIPG 4202/4885P2RX7 254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.