Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 13/20 | 0.55 |
| ▸ | CYP11B1 | P15538 | 8/20 | 0.55 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.48 |
| ▸ | NNMT | P40261 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16196012 | 1.00 | CYP11B2 (0.55) | CYP11B2CYP11B1ASIC3NNMTCYP2A6 | |
| SCHEMBL8385317 | 0.91 | ASIC3 (0.57) | CYP11B2CYP11B1ASIC3NNMTCYP2A6 | |
| SCHEMBL16196089 | 0.79 | NNMT (0.47) | CYP11B2CYP11B1ASIC3NNMTCYP2A6 | |
| SCHEMBL16195873 | 0.78 | CYP11B2 (0.48) | CYP11B2CYP11B1ASIC3NNMTALDH1A1 | |
| SCHEMBL1257921 | 0.78 | ASIC3 (0.52) | CYP11B2ASIC3NNMTALDH1A1PIK3C3 | |
| SCHEMBL8385558 | 0.76 | ASIC3 (0.61) | ASIC3NNMTPIK3C3 | |
| SCHEMBL16203253 | 0.76 | NNMT (0.44) | CYP11B2ASIC3NNMTPIK3C3 | |
| SCHEMBL15730767 | 0.76 | FEN1 (0.45) | ASIC3NNMTPIK3C3 | |
| SCHEMBL16195363 | 0.76 | CYP11B2 (0.52) | CYP11B2CYP11B1ASIC3NNMTPIK3C3 | |
| SCHEMBL16196626 | 0.76 | CYP11B2 (0.50) | CYP11B2CYP11B1ASIC3NNMTPIK3C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2991985-B1 | ALDOSTERONE SYNTHASE INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2018-06-13 | — | — | EP | disclosed |