Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 5/20 | 0.49 |
| ▸ | USP30 | Q70CQ3 | 12/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20239929 | 1.00 | UCHL1 (0.49) | UCHL1USP30MAPTMEN1KMT2A | |
| SCHEMBL17632190 | 0.93 | UCHL1 (0.49) | UCHL1USP30MAPTMEN1KMT2A | |
| SCHEMBL29992743 | 0.93 | UCHL1 (0.49) | UCHL1USP30MAPTMEN1KMT2A | |
| SCHEMBL17632185 | 0.93 | UCHL1 (0.49) | UCHL1USP30MAPTMEN1KMT2A | |
| SCHEMBL17632022 | 0.87 | USP30 (0.51) | UCHL1USP30MAPTMEN1KMT2A | |
| SCHEMBL31166693 | 0.87 | USP30 (0.51) | UCHL1USP30MAPTMEN1KMT2A | |
| SCHEMBL30513241 | 0.85 | UCHL1 (0.46) | UCHL1USP30MAPTMEN1KMT2A | |
| SCHEMBL17631922 | 0.85 | UCHL1 (0.46) | UCHL1USP30MAPTMEN1KMT2A | |
| SCHEMBL17632569 | 0.84 | USP30 (0.52) | UCHL1USP30MAPTMEN1KMT2A | |
| SCHEMBL17632566 | 0.84 | USP30 (0.52) | UCHL1USP30MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10392380-B2 | Compounds | MISSION THERAPEUTICS LIMITED (GB) | 2019-08-27 | — | — | US | disclosed |
| US-20180162852-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LIMITED | 2018-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180162852-A1 | NOVEL COMPOUNDS | UCHL1, UCHL3, UCHL5 | UCHL1 1/4885USP30 19/4885MAPT 2428/4885 |
| US-10392380-B2 | Compounds | UCHL1, UCHL3, UCHL5 | UCHL1 1/4885USP30 20/4885MAPT 2227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.