SCHEMBL202402

SCHEMBL202402

CNC(=O)n1c(NC(=O)OC)nc2cc(C)ccc21

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.49
TSHR P16473 1/20 0.49
AGPAT2 O15120 6/20 0.47
HPGD P15428 1/20 0.43
KDM4E B2RXH2 1/20 0.40
HSD17B10 Q99714 1/20 0.40
MEN1 O00255 1/20 0.39
HTT P42858 1/20 0.39
KMT2A Q03164 1/20 0.39
MCHR1 Q99705 1/20 0.37
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
P2RX3 P56373 3/20 0.35
KDR P35968 1/20 0.35
TEK Q02763 1/20 0.35
EGFR P00533 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
P2RX2 Q9UBL9 1/20 0.34
DYRK1A Q13627 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL203792 0.90 ALDH1A1 (0.49) ALDH1A1TSHRAGPAT2HPGDMEN1
SCHEMBL28952010 0.89 CYP1A2 (0.47) ALDH1A1TSHRAGPAT2HPGDKDM4E
SCHEMBL14809081 0.88 KDM4E (0.43) ALDH1A1TSHRAGPAT2KDM4EHSD17B10
SCHEMBL203934 0.84 AGPAT2 (0.47) ALDH1A1TSHRAGPAT2HPGDKDM4E
SCHEMBL202952 0.83 ALDH1A1 (0.68) ALDH1A1TSHRHPGDKDM4EHSD17B10
SCHEMBL11630270 0.81 ALDH1A1 (0.49) ALDH1A1TSHRAGPAT2HPGDKDM4E
SCHEMBL11705286 0.79 ALDH1A1 (0.47) ALDH1A1TSHRAGPAT2HPGDKDM4E
SCHEMBL203406 0.79 CYP1A2 (0.47) ALDH1A1TSHRAGPAT2HPGDKDM4E
SCHEMBL11766715 0.76 ALDH1A1 (0.42) ALDH1A1TSHRHPGDHSD17B10NPC1
Carbamic Acid SCHEMBL28379174 0.76 CYP1A2 (0.43) ALDH1A1TSHRAGPAT2HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 251 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3746505-B1 COMPOSITION, POLYMER COMPOSITE ARTICLE FORMED THEREWITH, AND METHOD OF PREPARING SAME DOW SILICONES CORP (US) 2024-06-26 EP disclosed
EP-3906245-B1 MULTIFUNCTIONAL ORGANOSILICON COMPOUND AND RELATED METHODS, COMPOUNDS, AND COMPOSITIONS DOW SILICONES CORP (US) 2024-05-29 EP disclosed
US-20240124709-A1 COMPOSITION, POLYMER COMPOSITE ARTICLE FORMED THEREWITH, AND METHOD OF PREPARING SAME DOW GLOBAL TECHNOLOGIES LLC 2024-04-18 US disclosed
EP-3645640-B1 SILICONE-POLYETHER COPOLYMER, METHOD OF PREPARING SAME, AND SEALANT COMPRISING SAME DOW SILICONES CORP (US) 2024-03-06 EP disclosed
US-11884821-B2 Composition, polymer composite article formed therewith, and method of preparing same DOW SILICONES CORPORATION (US) 2024-01-30 US disclosed
US-11820846-B2 Composition, method of preparing copolymer, and methods and end uses thereof DOW SILICONES CORPORATION (US) 2023-11-21 US disclosed
WO-2023215360-A1 SILICONE-POLYETHER COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS DOW SILICONES CORPORATION (US) 2023-11-09 WO disclosed
US-11807775-B2 Silicone-organic copolymer, sealants comprising same, and related methods DOW SILICONES CORPORATION (US) 2023-11-07 US disclosed
CN-116874967-A Composition, polymer composite article formed therewith, and method of making the same 美国陶氏有机硅公司 2023-10-13 CN disclosed
US-11760841-B2 Silicone-polycarbonate copolymer, sealants comprising same, and related methods DOW SILICONES CORPORATION (US) 2023-09-19 US disclosed
EP-1866366-A1 ORGANOSILOXANE COMPOSITIONS Dow Corning Corporation (US) 2007-12-19 EP disclosed
WO-2006106359-A2 ORGANOSILOXANE COMPOSITIONS DOW CORNING CORPORATION (US) 2006-10-12 WO disclosed
WO-2006106360-A1 ORGANOSILOXANE COMPOSITIONS DOW CORNING CORPORATION (US) 2006-10-12 WO disclosed
WO-2006106362-A1 ORGANOSILOXANE COMPOSITIONS DOW CORNING CORPORATION (US) 2006-10-12 WO disclosed
WO-2006107762-A1 ORGANOSILOXANE COMPOSITIONS DOW CORNING CORPORATION (US) 2006-10-12 WO disclosed
WO-2006106095-A1 ORGANOSILOXANE COMPOSITIONS DOW CORNING CORPORATION (US) 2006-10-12 WO disclosed
WO-2006106361-A1 ORGANOSILOXANE COMPOSITIONS DOW CORNING CORPORATION (US) 2006-10-12 WO disclosed
EP-0585587-B1 Fungiresistant polyorganosiloxane composition TOSHIBA SILICONE (JP) 1997-05-21 EP disclosed
US-5378406-A Benzimidazolylcarbamate, pyridyl oxide zinc salt TOSHIBA SILICONE CO., LTD. (JP) 1995-01-03 US disclosed
EP-0585587-A1 Fungiresistant polyorganosiloxane composition TOSHIBA SILICONE CO., LTD. (JP) 1994-03-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11820846-B2 Composition, method of preparing copolymer, and methods and end uses thereof BRS3, OXSR1, OXER1 ALDH1A1 3354/4885TSHR 566/4885AGPAT2 3218/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.